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Check out our spotlight article in Trends in Genetics written with Michael Berger highlighting the recently published method for genetic ancestry inference from cancer-derived data by Belleau et al (PMID: 36351074). authors.elsevier.com/c/1gowscQbJ7Wj1

Today our important study on air pollutants in the promotion of lung cancer has been published in nature led by Will Hill Emilia Lim Clare Weeden Swanton Lab ...Thread below🧵nature.com/articles/s4158…

Here's an early look at some of the research MSK physicians and scientists will present at the AACR annual meeting, kicking off this Friday. Keep checking back here to get the latest updates out of MSK. #AACR23 bit.ly/3KTifF7?utm_ca…

Today’s first presenter is Henry Walch, MS, of Memorial Sloan Kettering Cancer Center. #AACR23 Memorial Sloan Kettering Cancer Center

Congrats to Henry Walch Henry Walch, whose poster was selected for the #AACR23 press program. He presented novel insights into the genomic basis of racial disparities in #colorectalcancer. Learn more about his research. #crcsm mskcc.org/news/why-color…

Great science by Madison Darmofal (#5440) and Miika Mehine, Ph.D. (#5214) at the #AACR23 poster session, presenting novel insights from #MSKimpact tumor sequencing data. 💪🧬

People - I know it’s the last day of #AACR23 - but finish it w/ bang! Visit our Senior Scientist Moriah Heller Nissan, PhD in Section 13 (West side) poster #18 to see our OncoKB™ poster & here about the latest developments we’re working on.

New BIG OncoKB™ release people & we hv >7000 cancer mut! Since we gp mut such as truncating or exon deletion etc together this # is staggering! + ESR1 LBD in breast, KRAS G12C in PDAC & ERBB2 amp in biliary tract are all now std care biomarkers - ingrafitinib removed

How 2 MSK-developed #cancer #genetictests - MSK-IMPACT® (which uses a tissue biopsy to identify the best treatment) & MSK-ACCESS® (a blood test to detect a patient's response to treatment) - have helped revolutionize the way cancer is treated worldwide: bit.ly/3ptKeTR

.MSK Library feature: Unique Genomic Alterations & Microbial Profiles Id'd in Patients w/#GastricCancer of African/European/Asian Ancestry dx.doi.org/10.1097/SLA.00… Miseker Abate MD MPH Henry Walch Kanika Arora Chad Vanderbilt, MD Teng Fei Yelena Kemel Zsofia Stadler Smita Sihag Michael Berger

The publication of the whole genomes from the US AllofUsResearch cohort is great to see, but the choice of how to represent an overview of the genetic relationships has (rightly) drawn controversy, in particular how the concepts of ethnicity and race are mapped to it.

I've written about race, genetic ancestry, analyses of large biobanks, and human history gusevlab.org/projects/hsq/#… I'll summarize the key points here 🧵:

✨New paper alert Cancer Discovery✨ - GDD-ENS distinguishes 38 cancer types (>96% of patients) w/ high accuracy using routinely collected DNA sequencing data #MSKIMPACT and generalizes well to other gene panels w/o retraining - CNAs (arm/gene level) are key features for classification

Prior to the #AACR24 session on genetic ancestry, a good read is this Cancer Discovery "Genetic Ancestry Correlates with Somatic Differences in a Real-World Clinical Cancer Sequencing Cohort" doi.org/10.1158/2159-8…

Attending today's #AACR24 session on Genetic Ancestry? ICYMI in Cancer Discovery: Genetic Ancestry Correlates with Somatic Differences in a Real-World Clinical Cancer Sequencing Cohort Kanika Arora Michael Berger doi.org/10.1158/2159-8… Memorial Sloan Kettering Cancer Center

Have advances in precision oncology therapies benefited cancer patients from various ancestral backgrounds equally over time? Check out our poster at #AACR24 today, Apr 9 1:30pm, (Section 32, board 23) to find out. abstractsonline.com/pp8/#!/20272/p…

Great to meet Kanika Arora yesterday at #AACR24 - her work was featured in the AACR Journals collection on Cancer Disparities!

Genetic Ancestry–Based Differences in Biomarker-Based Eligibility for Precision Oncology Therapies Out on JAMA Oncology buff.ly/3C4yc9I This study investigates the impact of precision oncology therapies on patients with cancer from different ancestral backgrounds,

Beginning in 2019, fewer patients of inferred African ancestry were found to be eligible for treatment with FDA-approved precision oncology drugs compared with individuals with other inferred genetic ancestries. ja.ma/3WdisZ7

A new study led by MSK computational biologist Kanika Arora and MSK molecular geneticist Debyani Chakravarty, PhD 🇺🇦 uncovers why new precision oncology treatments benefit patients of some ancestries more than others. "We need to learn from patients from diverse and underrepresented