
Celeste Karch
@karchlab
Professor. Washington University School of Medicine. Genomics, stem cell models, molecular mechanisms of AD and other tauopathies. She/her. š¦Karchlab
ID: 844551350977474562
http://sites.wustl.edu/karchlab 22-03-2017 14:08:27
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Neuron Cell Reports Cell Reports Methods USBrainAlliance Specific targeting of brain endothelial cells using enhancer AAV vectors cell.com/neuron/fulltex⦠Neuron

Neuron Cell Reports Cell Reports Methods USBrainAlliance An AAV capsid proposed as microglia-targeting directs genetic expression in forebrain excitatory neurons cell.com/cell-reports-m⦠Cell Reports Methods




š New paper alert! Congrats Courtney Lane-Donovan and team on the latest publication in Alzheimerās & Dementia: "Tau phosphorylation at Alzheimer's disease biomarker sites impairs its cleavage by lysosomal proteases" š§ š§Ŗalz-journals.onlinelibrary.wiley.com/doi/10.1002/al⦠#Neuroscience #CWOW






Excited to share a new preprint out from the lab (biorxiv.org/content/10.110ā¦) by 1st-author Brittany Hemmer , a newly minted PhD from the lab! A brief thread on what we found (1/n):



The Celeste Karch demonstrate that MAPT mRNA and tau protein are expressed in microglia in human brains and in hiPSC-derived #microglia like cells. š§ š”Learn more in their new molecularpsychiatry study: go.nature.com/447xVwS
