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Kidney360’s mission is to publish scientifically rigorous research that includes content from all disciplines of kidney science. The editors have selected the following articles to highlight the outstanding quality and broad spectrum of published content from 2023

Editors' Choice: Effects of Dapagliflozin on EChOcardiographic Measures of CarDiac StructurE and Function in Patients with CKD This study addresses the effects of SGLT2 inhibitors on cardiac function in patients with CKD bit.ly/KID0006982022wk scottdavidsolomon Oxford Population Health (OxPop)

The CTCPR Trials & CIRL team summer dinner after a long day of ESC abstract rehearsals. With more than 25 accepted abstracts for this year’s ESC congress, it took the whole day to get throug all abstract presentations. Lucky to mentor so many bright and talented LEGENDS OF TOMORROW #ESC24

I’m very proud to have had the opportunity to mentor Caroline Espersen for >5 years. Caroline Espersen is one of the most talented people I’ve worked with and she is the coordinating PI on one of the most innovative RCT’s we are doing. Congratulations Caroline Espersen, this is very well deserved.

Congratulations 👏 to Katja and the rest of the amazing CTCPR Trials & CIRL team for finalizing recruitment of our DECODE-CKD trial. Results will be ready in 6 months. Please read more about the trial in the design paper. See link below 👇 journals.lww.com/kidney360/full…

Our amazing CTCPR Trials & CIRL fellows 🌟 will present 24 scientific abstracts at #ESC24 in London about the science we are generating at CTCPR Trials & CIRL. All abstract titles and times are displayed below.👇 Some of the projects will be published simultaneously with the conference. Stay tuned

For CKD patients, do you administer regular dose or high dose #influenza vaccine? 💉 Secondary analysis of DANFLU-1 in #JACC: bit.ly/3ADdUmD #ESCCongress CTCPR Trials & CIRL Tor Biering-Sørensen, MD, MSc, MPH, PhD Niklas Dyrby Johansen

Another simultaneous publication from the great CTCPR Trials & CIRL team. In this specific analysis Katja assessed the relative vaccine effectiveness of HD vs SD in patients with CKD in DANFLU-1. 👇 Published today in JACC Journals Sanofi @BiomedUCPH HerlevGentofte Hosp. RigsHeart 🫀🚨

This year’s CTCPR Trials & CIRL dinner at #ESC2024! We are increasing in size every year; this year was our largest ESC dinner ever (>40 people); including great friends and collaborators like avazir Harriette Van Spall, MD MPH 🇨🇦 Steve Greene Brittany Weber scottdavidsolomon Ankeet S. Bhatt, MD, MBA Sheila Hegde Nochioka Kotaro

Does high-dose influenza vaccine reduce clinical outcomes in people with CKD compared with standard-dose? On behalf of the DANFLU1 team, I just presented the preliminary subgroup analysis at the #ESCCongress. Read more 👇🏽 bit.ly/3ADdUmD Tor Biering-Sørensen, MD, MSc, MPH, PhD Niklas Dyrby Johansen CTCPR Trials & CIRL

ESC has come to an end. Below is a list with the simpub’s from the CTCPR Trials & CIRL team this year👇. Stay tuned, many more pubs soon! Nat Med: nature.com/articles/s4159… JACC: jacc.org/doi/10.1016/j.… JACC: jacc.org/doi/10.1016/j.… CircOut: ahajournals.org/doi/10.1161/CI… DOM: dom-pubs.onlinelibrary.wiley.com/doi/abs/10.111…

EASi-KIDNEY kicks off from ⁦Oxford Population Health (OxPop)⁩ (a new journey through 🇨🇳 🇺🇸🇨🇦🇲🇽🇧🇷🇦🇷🇦🇺🇳🇿🇯🇵🇰🇷🇹🇼🇲🇾🇮🇳🇩🇪🇮🇹🇵🇹🇬🇧 begins 🥂 ). 10,999 more pts to recruit…gulp! Thanks+++ to all its supporters: u r guardians of randomization & the mission 4 larger simpler trials ouh.nhs.uk/news/article.a…

Effects Of Dapagliflozin On Echocardiographic Measures Of Cardiac Structure And Function In Patients With Chronic Kidney Disease: The DECODE-CKD Trial #ACC25 dapagliflozin significantly reduced LV mass index to a greater extent than placebo after 6 months of therapy

DECODE-CKD: ♥️In pts w CKD, dapagliflozin reduced LV mass at 6 mo vs placebo ♥️No effect on LV systolic function or LV/LA size ♥️Drop in eGFR was 🔗 w regression in LV mass #ACC25 American College of Cardiology ACC Media Center #CardioTwitter

Great presentation of the DECODE-CKD main results at #ACC25 📍Chicago N=222 CKD patients randomized 1:1 to data or placebo At 6 mths 📆, LV mass index was significantly ⬇️ by 8g/m2 in the dapagliflozin group 💊 Tor Biering-Sørensen, MD, MSc, MPH, PhD CTCPR Trials & CIRL

It was a great honor to present our DECODE-CKD trial today as a LBCT presenting at American College of Cardiology on behalf of my brilliant research fellow Katja (who gave birth to a beautiful baby girl last week) and the rest of the amazing CTCPR Trials & CIRL team! Publication out soon! Stay tuned.

❗️Among 222 pt with CKD, dapagliflozin favorably reduced LV mass index compared to placebo after 6 months of therapy Proud to see the results of our DECODE-CKD on the late-breaking stage, presented brilliantly by my mentor prof. Biering-Sørensen.