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Die 24. Jahrestagung der NOA (Neuroonkologische Arbeitsgemeinschaft) findet am 10. und 11.11.2022 in Heidelberg statt. Wo? Großer Hörsaal der Kopfklinik Im Neuenheimer Feld 400 69120 Heidelberg Zur Registrierung: ukhd.de/noa #Neuroonkologie #Heidelberg #UKHD

Happy to share our work on TRAF7muts in meningioma/congenital heart disease. Shared genetics can be traced to common neural crest origin. Mutations disrupted scaffold protein function and caused cilia defects. Yale Department of Neurosurgery Sheng Chih Jin @HdNeurooncology pnas.org/doi/10.1073/pn…

We are extremely grateful to the foundation, all great clinicians and scientists as well as patients supporting science. We aim at making further big steps in research and treatment of brain tumors. DKFZ Uni Heidelberg Universitätsklinikum Heidelberg

The International Primary CNS Lymphoma Collaborative Group (IPCG), co-founded by Tracy Batchelor, Franco Cavalli, and James Armitage in 2002, held its 21st annual meeting at the 2023 American Society of Hematology conference in San Diego, California last Friday.

A great team effort: LBCL is getting complicated! R/R guideline to follow.... doi.org/10.1111/bjh.19… Andrew Davies Sridhar Chaganti Pam McKay Toby Eyre Sally Barrington Andrea Kuhnl Kate Cwynarski #GMcIlroy #CBurton #TIllidge @NKalakonda LymphomaAction BSH - Haematology

Profiling a case of secondary T cell lymphoma following anti-CD19 #CARTcells suggests this was not caused by CAR insertional mutagenesis, with analysis indicating low secondary TCL risk after treatment Guido Ghilardi Marco Ruella Ruella Lab Penn Medicine nature.com/articles/s4159…

Important study and a promising novel therapeutic avenue for EBV associated DLBCL. ORR was 51% in a pretreated PTLD population. Combination with targeted therapy may be key given CR rate of 28%? No firm conclusions about CNS disease yet. @HdNeurooncology

As part of my PhD thesis Wolfgang Wick 🇪🇺 lab DKFZ, Universitätsklinikum Heidelberg, Uni Heidelberg, @HdNeurooncology we investigated the cellular and molecular composition of tumor microtube networks in #Glioblastoma (1/6) The manuscript is hot off the press Nature Communications: nature.com/articles/s4146…

.Dirk Hoffmann Wolfgang Wick 🇪🇺 et al. at DKFZ @HdNeurooncology combine a dye uptake method and #scRNAseq to infer a tumor microtubule connectivity signature in #glioblastoma, find CHI3L1 as a driver #GBM #Neurooncology #CancerResearch Cancer at Nature Portfolio nature.com/articles/s4146…

Forschende des Universitätsklinikum Heidelberg und DKFZ identifizieren genetische Signatur, die für Tumorzellen von #Glioblastom|en typisch ist. Durch die Gensignatur lassen sich neue Therapien überprüfen. Zudem decken sie mögliche Schwachstellen der Tumorzellen auf. ➡️ t1p.de/fo0jf

Today, NEJM published our clinical study of a novel #CARTCell in patients with #Glioblastoma. Early results with CARv3-TEAM-E suggest safety and bioactivity. Special thanks to all collaborators MGH Neurosurgery and Mass General Cancer Center! nej.md/3VnjUIq

Excited to share the MGH institutional experience of r/r neurolymphomatosis managed with CD19-CAR. Treatment was well tolerated and showed promising efficacy. Findings suggest CD19-CAR may sufficiently penetrate the blood nerve barrier. MGHNeuroOncology MGH Neurology @HdNeurooncology