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The implications of this finding, intersect with the role of chromatin organization and dynamics in regulating post-transcriptional RNA splicing, viral interference by herpesviruses, and potentially the pathogenesis of complex chronic conditions such as ME/cfs. FYI Bhupesh K Prusty

📢 NIG Postdoc Fellowship Call! nig.ac.jp/nig/career-dev… We’re seeking motivated postdocs to join our lab.🧬🔬 We study chromatin behavior in living cells using live-cell imaging and quantitative analysis: science.org/doi/10.1126/sc… doi.org/10.2183/pjab.1… Interested? Please apply!

Check out our review article on noncanonical nucleosomes, which differ from canonical nucleosomes in their histone composition and DNA wrapping. The article highlights recent insights into their structural and functional diversity. sciencedirect.com/science/articl…

1/ Super excited to share my first preprint from ASHansen Lab! We used MINFLUX to track chromatin (H2B-Halo and Fbn2 locus) at an unprecedented 200 μs, then combined it with SPT to span μs-minutes (H2B) or SPT & Super-Res Live-Cell Imaging (SRLCI) to span μs-hours (Fbn2)

(1/13) Thread on Matteo Mazzocca Domenic Narducci Simon Grosse-Holz Jessica Matthias new preprint Q: how does chromatin move? Using MINFLUX, SPT & SRLCI, we track chromatin dynamics across 7 orders of magnitude in time to provide some answers biorxiv.org/content/10.110…

Excited to share our new paper on structures of native transcribing RNAPII inside human cells Nature Communications!!😆We isolated RNAPII by ChIP and visualized their structures by cryoEM. Transcribing RNAPII are visualized without reconstitution! Check out! 1/5 doi.org/10.1038/s41467…

Ghosh, Prasad et al. IISER Kolkata elucidate the role of ecdysone signaling in orchestrating the removal of nurse cells by transforming the epithelial follicle cells to a phagocytic fate during late #Drosophila #oogenesis. hubs.la/Q03pvtf90 #Development #CellDeath

New findings in Science demonstrate that successful mitosis may draw on more mechanisms than commonly assumed. Learn more in a new #SciencePerspective: scim.ag/43MSoYJ

🚨 New paper alert! 🚨 Can we simultaneously achieve deep, high-res, large field-of-view imaging without the usual trade-offs? 🤔 🧬🔬 YES: #DNA_PAINT + Spinning Disk Confocal + Optical Photon Reassignment (#SDC_OPR)! #SuperResolution 📄 nature.com/articles/s4146… Nature Communications 🧵👇

Our new paper has been published! In this study, we revealed the mechanism by which the efficient transcription by RNA polymerase II is accomplished on nucleosomes containing a histone variant H2A.B. #cryoEM embopress.org/doi/full/10.10…

I attended the 28th 3R workshop 2025 in Atami! At this workshop, I discussed with many researchers who have various research background (not only cell biology, but also molecular genetics). I enjoyed the discussion during the presentation, lunch, dinner, and night party!

Zucchini timelapse 🌱🕰️🌿

Our new paper is finally out, uncovering the distribution of H2A variants in mouse oocytes and the epistasis between H2A.Z and H3K4me3 across intergenic regions. nature.com/articles/s4159… Short summary in thread↓↓ (1/9)

Our new review paper is out @ JMB!　🧬 Katsuhiko Minami Adilgazy Semeigazin, MSc よしこりあん discuss DNA accessibility in euchromatin and heterochromatin in living cells. 📘 Free access: authors.elsevier.com/a/1lHgb54HFZNbb 🔗 Also, check our previous paper on nucleosome motion: science.org/doi/10.1126/sc…

Our review paper has been published in JMB! We described the work of our postdoc, Dr. Katsuhiko Minami, about specific repli-histo labeling of eu- and hetero- #chromatin with implications for #transcription. We thank our professor, Dr. Kazuhiro Maeshima, for supporting us!

Happy to share our recent study, spearheaded by Qianhua Xu and Chunyi Huang, on the essential role of H2A.Z in mouse oocyte development, published back-to-back with work from Azusa Inoue's team Azusa Inoue | 井上梓 nature.com/articles/s4159…

🧵Thrilled to share my first-author paper published in J Cell Science Title: A single-chain antibody-based AID2 system for conditional degradation of GFP-tagged and untagged proteins (1/🧵) doi.org/10.1242/jcs.26…

Congratulations!