And we're live Broad Institute with high capacity #COVID19 testing The idea to convert the sequencing powerhouse into high throughput testing developed March 9. 2 wks later we were live! Thanks entirely to the massive efficient efforts of the Broad team! broadinstitute.org/news/how-broad…

With widespread adoption of single-cell-omics technologies, developmental biologists are increasingly relying on the use of “gene expression trajectories” to study cell differentiation. What is the difference between a trajectory and a lineage? (1/4)

A timely overview of lung regeneration Cell Stem Cell. cell.com/cell-stem-cell…

It's my 9th year Addgene. Tis is the most challenging time we've faced as a nonprofit, but may also be the most promising. Finally bridging the academia/industry chasm for plasmid sharing. Sign up to be notified when the industry collection expands info.addgene.org/industry-distr…

Graduating PhD student looking for an industry postdoc? Check out this opportunity studying cell death pathways in lung disease Novartis Science. Fascinating and complex science, great mentorship, opportunity for publications, exposure to industry! novartis.com/careers/career…

Interested in modeling SARS-CoV-2 infection with iPSC-derived lung cells? Check out this new bioRxiv from Kristy Abo featuring many others CReM! #COVID

Drs. @FinnHawkins, Ruobing Wang, and CReM colleagues present a human #iPSC-derived airway epithelial platform, composed of the major airway epithelial cell types, that is permissive to #SARS-CoV-2 infection. 🫁 Read their findings: 📎 bit.ly/3Ilfx77

Very excited to share our new preprint, leveraging pooled CRISPRi screen and Targeted DamID to study transcription factor function using primary human foetal lung organoids. biorxiv.org/content/10.110…

Seeking curious PhD lung immunologist for Principal Scientist role Novartis Science to study link between genetics & immunity in lung disease. We are a passionate team driven to build transformative therapies for patients. Please RT & reach out w q’s! novartis.com/careers/career…

Airway cillia in green, a mucin ( guess which one 👀) in blue. #airway #cilia #b3d #lovevwhatyoudo #lungs #microscopyinspires work in progress

How do cultured primary lung cells (AT2) compare to fresh and iPSC derived? Our latest work asks this question: just posted at biorxiv from the Labs of @kottond Barry Stripp and Carla Kim Lab #awesomecollaborators biorxiv.org/content/10.110…

Are you a recent/upcoming PhD grad passionate about understanding epithelial cell fate & curious about industry? New postdoc position open in gene regulation and chromatin biology in lung epithelial differentiation Novartis Science in Cambridge, MA, USA. novartis.com/careers/career…

Woohoo. Our paper is finally out today in nature !! A quick 🧵 with the highlights!

Congratulations to Maria C. Basil and the whole team! Honored to have been a part of this beautiful work. Check out her thread summarizing this cool paper ⬇️

Congrats to Maria C. Basil and @leoviral3 from MorriseyLab on this fantastic new paper just out in nature! Featuring some cool #iPSC models at CReM with Darrell Kotton and Katie McCauley! Read more here: nature.com/articles/s4158…

The absolute best UMAP discovery at FASEB Lung Epithelium Meeting: Darrell Kotton presents the „Fire Breathing Chicken“ identified in single cell datasets from jon kropski & team. Fantastic evening finale after an exciting day full of superb talks & discussions science!

It was amazing to spend some time with my #CReMFamily at FASEB Lung this past week! Feeling inspired by new science and old friends 🫁

Excited to share our new paper from Allon Klein Lab building an in-depth molecular profile of how 🫁 cells respond to signaling cues! biorxiv.org/content/10.110… Co-author extraordinare Kalki Kukreja unpacks the details below 👇

Fascinating work as always from shouwen wang & colleagues building incredible tools to dissect biology at single cell resolution.

McCauley et al. map the response of the airway epithelium to diverse signaling pathways, providing a systematic framework for studying signaling responses in regenerative tissue. Allon Klein Lab Katie McCauley cell.com/cell-systems/f…