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King's College London DRIVE-Health is offering 10 PhD studentships in Data-Driven Health (deadline April 19th). Projects 7 and 42 (drive-health.org/apply/) are with my group, co-supervised with Claire Steves and Alan Hodgkinson

Recruiting for a 4-year BBSRC-funded PhD studentship in computational genomics of human skin ageing at King's College London in collaboration with Unilever; co-supervised by Kerrin Small and David Gunn. UK/EU fees covered. Deadline 15 Oct 2020. findaphd.com/phds/project/r…

**New!** London Genetics Network - online launch meeting 4th Dec 2020 - early career poster prize - great speaker line up - all London human geneticists welcome - forum to discuss network's remit Register here: eventbrite.co.uk/e/launch-meeti… PLEASE RT

We conducted a transcriptomic survey to study properties of escape from X-inactivation across tissues and cells in female twins. @A_L_Roberts alesssia | @[email protected] Julia E Moustafa Mario Falchi Kerrin Small TwinsUK research biorxiv.org/content/10.110…

Our paper investigating ACE2 gene expression in adipose tissue across three cohorts is now online at International J Obesity Work led by Julia E Moustafa in collaboration with Anne Jackson, Li Guan, Sarah Brotman Karen Mohlke Laura Scott and others nature.com/articles/s4136…

We're recruiting a Chair in Population Health Sciences & HoD of Population Health Sciences. Population Health is a major new strategic priority for King’s & we're looking for an innovative & committed leader. Deadline: 14 July 🗓️ Apply 👇 jobs.ac.uk/job/CQO420/cha…

Our paper led by @A_L_Roberts on skewed X chromosome inactivation and its relationship with molecular and cellular measures of aging, cardiovascular disease risk, and cancer diagnoses is online at @elife doi.org/10.7554/eLife.…

Our paper led by Antonino Zito investigating variation in escape from X-inactivation across tissues, individuals and twin pairs is now published in @PlosGenetics dx.plos.org/10.1371/journa… Many thanks to @A_L_Roberts alesssia | @[email protected] Julia E Moustafa Mario Falchi TwinsUK research

Excited to share a local maximum of my grad school roller coaster ride: our paper “The origins and functional effects of postzygotic mutations throughout the human life span” is now published in @sciencemagazine: science.org/doi/10.1126/sc…. 1/4

Our paper in collaboration with Mina Ryten and led by Karishma D’Sa nature.com/articles/s4159…

I am excited to share our preprint describing a collaborative effort to identify conditionally distinct signals in the largest adipose eQTL dataset to date (AdipoExpress)! Kerrin Small, Karen Mohlke, Laura Scott, Julia E Moustafa, Michael Love, and others. 1/8 biorxiv.org/content/10.110…

Several group leader positions available in Dept. of Medical and Molecular Genetics at King's College London (from lecturer to professor) - an exciting opportunity to join a thriving human genetics community and build something brilliant! tinyurl.com/4c8z8hnw

Excited to share our new preprint in which we address: (1) Accurate sequencing of sperm at scale (2) Positive selection of spermatogenesis driver mutations across the exome (3) Offspring disease risks from male reproductive aging [1/15] medrxiv.org/content/10.110…

Excited to share our latest work. We introduce an improved version of NanoSeq, a duplex sequencing protocol with <5 errors per billion bp in single DNA molecules, and use it to study the somatic mutation landscape of oral epithelium in >1000 people. 1/n medrxiv.org/content/10.110…

II'm excited to finally share our study on the mutational landscape and selection dynamics in sperm, now live on medRxiv: medrxiv.org/content/10.110…. We explored how positive selection impacts mutation rates, especially with age. Here’s a quick thread on our findings! 🧵👇

Very excited to share that our manuscript on cis-eQTL analysis of adipose tissue gene expression in 2,344 samples is now out in Nature Genetics rdcu.be/d5ov4 See thread from lead author Sarah Brotman below