Alokkumar Jha
@knowingalok
Assistant Professor (Neuroscience) @WeillCornell #datascience #genetics #computational biology opinions are my own.
ID: 1515845009848868867
https://vivo.weill.cornell.edu/display/cwid-alj4008 18-04-2022 00:09:57
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We show that #CHIP is a novel risk factor for ICI myocarditis 🫀, similar to risk of dual ICI therapy. This has implications for evaluation of CHIP in those planned for ICI therapy & tailoring monitoring strategies. rdcu.be/d1BcT #CHIP #Immunotherapy Yale University
In >2100 pts on ICI Yale New Haven Hosp, adverse 🫀 outcomes: 44% developed ACE; this⬆️risk of ☠️ 2.7x. In favor of bl imaging in European Society of Cardiology cardioonc guidelines, 26% had abnl LVEF/GLS on echo B4 ICI. CMR B4 ICI: 43% had LV dysfxn, 50% RV dysfxn, 32% w/LGE, 9% w/⬆️T2 tinyurl.com/4rbepe3t
An early holiday gift 🎁Excited to have been involved in this work led by Michael Snyder, PhD & Tracey McLaughlin & championed by Ahmed A. Metwally, PhD The utility of at home continuous glucose monitoring coupled with machine learning to predict metabolic subtypes. nature.com/articles/s4155…
The potential for using continuous glucose sensors and #AI to differentiate types of glucose dysregulation in people with Type 2 diabetes or pre-diabetes nature.com/articles/s4155… @NatBME SnyderLab: Personalized Multi-Omics
~567 million people are affected w/diabetes in the 🌎Congrats Ahmed A. Metwally, PhD, Alokkumar Jha & team on this seminal work Nature Biomedical Engineering, showing that not all diabetes is the same! Insights on how to target DM based on mechanism #polygenicrisk #ML
Leveraging graph networks & game theory to predict cancer therapy cardiotoxicity. Congrats Avnith, winning a @regeneron Society for Science scholar award for his work in our lab, Co-mentored w/@kowingalok! Future in science is bright; great ROI➡️society tinyurl.com/4pnvvs38
Look forward to sharing our studies American College of Cardiology 2025 in Chicago! Yale Cardiology Yale University Yale School of Medicine Ruben Mora Ruey Hu, MD, MPH Patrick Kwaah Mandana Chitsazan, M.D. Alokkumar Jha Yale CVRC
David Liu receives Breakthrough Prize in Life Sciences. David R. Liu is honored for the development of base editing and prime editing, two gene editing technologies transforming medicine. Breakthrough broadinstitute.org/news/david-liu…
Absolutely spot on, Dr.V.Mohan sir. The risk is real, One survey found that 60% of those who relied on AI alone misjudged the seriousness of their symptoms, leading to delayed care and severe complications. AI can support but should never replace expert medical judgment. Thank
Congrats Alokkumar Jha on cutting edge work using deep learning of genomics🧬 to id risk for Alzheimer’s disease, providing long sought after mechanistic insights as to why GLP1RA⬇️risk! Highlighted by Dr Ross’ presidential address American Neurological Association #ANA2025 Eric Topol🧠↔️🫀 coming!
Congrats @knowingalok on this innovative work showing brain 🧠-heart ❤️ interactions: using a radiogenomics approach to id brain 🧠 imaging features to predict future CVD & vice versa, revealing genomic 🧬 associations and therapeutic targets 🎯 AHA Science #AHA25