Kristen R Maynard
@kr_maynard
Neuroscientist @LieberInstitute using a cross-species approach to study cell type and circuit-specific gene expression changes in psychiatric disease.
ID: 1176652741944446977
25-09-2019 00:20:58
411 Tweet
432 Followers
176 Following
Congrats Sean Maden! Glad to be a part of this project!
Very excited to share new work where we used #snRNAseq and #spatial #transcriptomics to better understand the molecular landscape of the human hippocampus (HPC)! Huge thanks to Erik Nelson CMM JHU & MadhaviTippani Lieber Institute who led the work! 🔗 doi.org/10.1101/2024.0…
New paper on single-cell genomics & regulatory networks for 388 human brains just out in Science Magazine. Neat stuff on single-cell QTLs, cell-to-cell communication, & DL models simulating drug effects (science.org/doi/10.1126/sc…) #PsychENCODE24
🔥 Hot off the press our paper on systems biology profiling of #PTSD and #MDD across brain 🧠, cell-types 🫧, and blood🩸 is out in Science Magazine as part of #PsychENCODE24. Tap below for the full tweetorial by SysBioStress - Daskalakis Lab 💡science.org/doi/10.1126/sc…
Delighted to share that our data-driven molecular map of the DLPFC is now out in Science Magazine as part of a collection of #PsychENCODE studies. Grateful for the opportunity to contribute to this collective effort to better understand the molecular basis of brain disorders.
So happy I just presented one of my Lieber Institute projects about transcriptomic changes in 🐀 rat #habenula and #amygdala 🧠 after chronic fentanyl self-administration 💉together with Ege Yalcinbas at the 2024 NIDA meeting. NIDAnews Thank you for inviting me Kristen R Maynard!
Very excited that my meta-analysis of telomere length GWAS and experimental validation showing that POP5 and KBTBD6 are human telomere length regulation genes is out in Nature Communications! Shout out to my mentors Alexis Battle and Xxx sixy porn nature.com/articles/s4146…
Staff Scientist position available in our Division to manage operations in Lieber Institute Imaging Core Facility. Responsibilities include providing training on and managing equipment as well as providing consultations on experimental design and image analysis.
Very happy to share that my big paper from my postdoc with Paul Kenny, PhD is out today in Science! A few highlights below... science.org/doi/10.1126/sc…
I'm very excited to share my first postdoc preprint with Boyi Guo 郭博逸 and Stephanie Hicks, PhD! Here we preset SpotSweeper - the first spatially-aware quality control methods developed for spatial transcriptomics. 🧵 biorxiv.org/content/10.110…
Very excited to share this new preprint led by the super talented Kasey Brida. We started by asking what marks drug-activated ensembles and stumbled onto a surprising answer that identified a key regulator of neuronal excitability and reward. A brief 🧵... biorxiv.org/content/10.110…
Congratulations to all the Kavli NDI Distinguished Fellowship awardees. We are thrilled to support bold innovative transdisciplinary research, bridging #Neuroscience, #Engineering and #Data Science. The Kavli Foundation Kishore Kuchibhotla Dr. Jean Fan Justus Keri Martinowich Reza Kalhor
So happy to share our latest preprint from the circuits team in Keri Martinowich lab in collaboration with Gregory Carr. Thanks so much to Suhaas S. Adiraju, Jason Rehg and everybody that participated in this fun project. Now what's on the preprint.....
🚨Preprint alert🚨 Excited to share a commentary on opportunists and challenges in integrating spatially resolved #Transcriptomics (#SRT) data across tissues 🧠 and individuals 🧑🤝🧑! Co-led with Wodan Ling from Weill Cornell Medicine Population Health Sciences 🔗: arxiv.org/abs/2408.00367 🧵👇
Is your tissue larger than a 10x Genomics Visium capture area? If you need to stitch together the images but also the gene expression data, check our new preprint describing #visiumStitched We also shared example postmortem human brain data (3 samples) doi.org/10.1101/2024.0…
Bringing my account back to life just in time for #FluorescenceFriday with a peek at our preliminary dive into the human LC🔵in AD. Glials & microvessels surrounding tangles - let the adventure begin into their -omics! Major credit to Heena Divecha for the perfect slice!
Division of Translational Neuroscience Lieber Institute will be at #SfN24! Presentations span mice, monkeys and humans from molecular to cellular through circuits and behavior. If you are interested in what we do, please stop by! Jason Rehg Michael Totty @R_Phillips_3rd Yufeng Du 杜御风
![26 years after Larry Swanson emphasized “the amygdala is neither a structural or functional unit” we used sn-RNAseq to answer the question:
“What is the [primate] amygdala?”
Check out the preprint 👇
biorxiv.org/content/10.110…](https://pbs.twimg.com/media/GaPv4fYWEAIJbXi.jpg "Vincent Costa (@vincentcostaphd) on Twitter photo 26 years after Larry Swanson emphasized “the amygdala is neither a structural or functional unit” we used sn-RNAseq to answer the question:
“What is the [primate] amygdala?”
Check out the preprint 👇
biorxiv.org/content/10.110…")
I’m excited to share my latest postdoc project with you all! This was a dream team collaboration co-led by Rita Cervera and Svitlana Bach. We also developed web apps that allow anyone to easily explore the data, found in the GitHub repo below 👇🏻 github.com/LieberInstitut…