New work in 'The role of epigenetics in insects in changing environments' Special Issue! The diapausing mosquito Culex pipiens exhibits reduced levels of H3K27me2 in the fat body: doi.org/10.1111/imb.12… #Epigenetics #Culex #Diapause Michael Goodisman

In a recent Cell Stem Cell paper, the authors write the following about this UMAP: "bEPI and bTE derivatives were separated along UMAP-1, while trophoblast progenitor (bTE and bCTB) and differentiated cell types (bEVT, bSTB, and bPrSyn) were separated along UMAP-2" 👀👀👀👀 1/🧵

Multi-omic underpinnings of epigenetic aging and human longevity nature.com/articles/s4146…

What gets erased when you integrate #singlecell data across samples/studies, and can you get it back? When samples are from e.g. healthy & disease, should you simply massage cells together? FINALLY, I feel we can answer this question: doi.org/10.1101/2023.0…

ChromGene: gene-based modeling of epigenomic data | Genome Biology genomebiology.biomedcentral.com/articles/10.11… #Bioinformatics

Enjoying the vaccine masterclass at Duke-NUS Medical School. Appreciate Eng Eong Ooi for hosting, and having the opportunity to catch up with Philippe Buchy is just priceless!

A tribute to the late Emeritus Professor Chan Soh Ha penned by Eng Eong Ooi Emeritus Professor Chan Soh Ha, a clinically trained immunologist and a Fellow of the Academy of Medicine, Singapore passed away on 7th June 2023. The late Prof Chan had many achievements in a remarkable

"We developed ggkegg, an R package that integrates KEGG information with ggplot2." academic.oup.com/bioinformatics… github.com/noriakis/ggkegg

Benchmarking integration of single-cell differential expression buff.ly/3NVvyFs

Online Now: Lactate activates the mitochondrial electron transport chain independently of its metabolism dlvr.it/SxtWdP

The best R packages for data visualization r-graph-gallery.com/best-dataviz-p… via Yan Holtz #dataviz #rstats

Postdocteral fellowship opportunity for candidates from ASEAN countries to work in Singapore ➡️ snas.org.sg/saseaf

Ten quick tips for deep learning in biology buff.ly/3FDVrFY

Predicting transcriptional outcomes of novel multigene perturbations with GEARS buff.ly/3saDBr7

I'm teaching decision trees in my #MachineLearning course today. Simple models, but we can build to random forest & gradient boosting, powerful! 'First learn the tree, then you can comprehend the forest.' Here's my interactive #Python #dashboard on #GitHub @

In this perspective piece in ⁦PLOS Biology⁩, ⁦we discuss the importance of integrating T cell immunity as a measure of vaccine efficacy, when developing future vaccines for pandemic preparedness. ⁦Eng Eong Ooi⁩ journals.plos.org/plosbiology/ar…

aPEAR: an R package for autonomous visualisation of pathway enrichment networks | Bioinformatics academic.oup.com/bioinformatics… #Bioinformatics

Out today in Nature Biotechnology! PhD students & postdocs: there's a trick – overlooked and underused – for having new ideas in the creative process. Talk science 1 on 1 with a science buddy that you trust and think of it as an improvisation. nature.com/articles/s4158…… Martin Lercher

Guide to Effect Sizes and Confidence Intervals buff.ly/48GrUrB #rstats

Housekeeping & Reference Transcript/HRT Atlas v1.0 database: Find👤🐭Tissue-specific #HouseKeepingGenes Based on #GTEx #ARCHS4 housekeeping.unicamp.br qPCR primers😁 +way more gene-specific regulatory data🤠 Bidossessi Wilfried Hounkpe @NAR_Open 2021 academic.oup.com/nar/article/49…