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Heads up: terraforming Mars isn’t just sci-fi, it’s a real possibility that’s possible with today’s technology. Mars could be green in MY lifetime. 🚀 🌼 What’s stopping us? We need a lot more real research into how to do it right. Don’t nuke Mars! 👇

We hosted the ARIA Summit this week, so it seems a good time to reflect on the progress we've made over the last two years... 1/ ARIA is taking a new approach to funding breakthrough R&D to catalyse new trillion-pound industries anchored in the UK 🇬🇧 - a thread...

Perfect intersection of AI, digital dollar rails and world-class team. Excited for this journey.

How it starts... The first discovery from an AI Scientist and lab in the loop.

FutureHouse's goal has been to automate scientific discovery. Now we used our agents to make a genuine discovery – a new treatment for one kind of blindness (dAMD). We had multiple cycles of hypotheses, experiments, and data analysis – including identify the mechanism of action.

Today, we are announcing the first major discovery made by our AI Scientist, a new way to treat dry macular degeneration. Our AI Scientist did all the parts of this project autonomously, except literally running the wet lab experiments and writing the paper. If you want to work

A project we started a long time ago with Michael Pieler, Philippe Schwaller (he/him) and many others is now on Arxiv: The ChemPile - a massive dataset for training chemical foundation models.

A few years ago, it was 180,408 data points. Now it's 33,599,731. The most detailed view yet of how microbes influence one another is at our fingertips. concertobio.com/press/concerto…

"We've now funded almost 200 different projects up and down the UK… if true, they change the entire future of the UK and are consequential to the world." Our CEO Ilan Gur joined Katie Prescott + The Times and The Sunday Times Tech Podcast. Listen here: link.aria.org.uk/ttp-x

Devstral is the number one model on Hugging Face today 🎉 Thanks everyone for the support! huggingface.co/models

Last week, Meta released OMol25/UMA, a massive dataset of QM calculations and a set of models trained on the dataset. Over the past week, we've spent a lot of time benchmarking, hosting, and running these models. We wrote a post summarizing what we've learned (link below):

We’re going on a national listening tour to meet directly with pharmaceutical and biotech CEOs. This is a chance for the FDA to listen and gather feedback from those at the front lines of discovery. We are committed to strengthening a regulatory environment that enables

This past week, I attended a meeting with the leadership of Convergent Research focussed research organizations. It was an uplifting and inspirational meeting ! A meeting centered on bold research motivated by compelling visions: 🚀 nature.com/articles/d4158…

will be in sf latter half of june! very excited to take a waymo again pls dm if i can sleep on your couch from june 16th-23rd ❤️ i will bring you a gift in exchange + buy you dinner

The grugbrained developer is on our mandatory cultural reading list. Inspired by it, I wrote up some general learnings from ~1.5 years as CEO of FutureHouse, on the topic of "How make tribe strong and be less confuse." Maybe useful, maybe not.

The war on science in the US is already affecting private sector research like AlphaFold. Bears repeating but the private sector builds on top of things created by academic research for the public good. This hurts everyone.

Really thoughtful piece from Niko McCarty about bridge recombinases. Learn more about the discovery and engineering of these incredible systems in our papers: Discovery: nature.com/articles/s4158… Structural Characterization: nature.com/articles/s4158… Human cell editing:

The peer-reviewed version of expansion in situ genome sequencing is now out in Science! The news is bittersweet – when we first revealed this last September, I never guessed it would be my final paper in academia, but a lot has changed. A few parting thoughts:

Matt Durrant Send me an email if any want to work at FutureHouse!

A few thoughts. (1). Scenario planning is cheap. It is worth thinking about what we would do in the event of labor market disruptions, even if we attach a small percentage chance to any particular scenario occurring. Jason Furman