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Interested in automating e-chem? Then... #GoWithTheFlow! In the first ChemRxiv of my independent career, we present an automated, electrochemical flow platform for library synthesis and DoE optimization. A fruitful collab. with Merck. Check it out! chemrxiv.org/engage/chemrxi…

High-throughput experimentation of mAb decapping guides phosphine reductant choice and improves one-pot decapping/conjugation conditions. @emmertlab #merckchemistry go.acs.org/bX3

Scale-Up of Continuous Metallaphotoredox Catalyzed C–O Coupling to a 10 kg-Scale Using Small Footprint Photochemical Taylor Vortex Flow Reactors 🔓 doi.org/10.1021/acs.op…

Excited to share our work (Eunsung Lee) in collaboration with Prof. Tae-Lim Choi's group! Air-stable ruthenium catalysts with tethered CAAC ligands for REMP. A heartfelt thank you to the reviewers and editor for their invaluable advice! doi.org/10.1021/jacs.4…

Enantioselective Synthesis of α-Aryl Ketones by a Cobalt-Catalyzed Semipinacol Rearrangement (Craig P. Johnston and co-workers) @TheJohnstonLab St Andrews School of Chemistry #openaccess 🔓 onlinelibrary.wiley.com/doi/10.1002/an…

Delighted to contribute some thoughts to this wonderful article in Chemistry World on putting fluorine in drug molecules along with Timothy Noël, Gouverneur Group, David O'Hagan, and Rob Young! Check it out! chemistryworld.com/features/putti…

Our synthesis of the bisnortriterpenoid rubriflordilactone B, which features a [2,3]-Wittig−Still rearrangement, a Friedel−Crafts cyclization and an E1cB reaction/transesterification/oxa-Michael addition cascade, is now out in J. Am. Chem. Soc. : bit.ly/430IyCx

Hot off the press! 🔥We review the use of carbamoyl fluorides as a platform to explore fluoride-enabled reactivity. Just accepted in SYNTHESIS Journal Chemistry at Thieme. Congrats, Maryam! The Le Group thieme-connect.com/products/ejour…

Please check out our new achievement led by Dr. Jo: Size‐Programmable Matteson‐Type Annulation: Construction of Spirocycles from Simple Cyclic Ketones - Jo - Angewandte Chemie International Edition - Wiley Online Library onlinelibrary.wiley.com/doi/epdf/10.10…

Have a look at this report of the first remote hydrogermylation of alkenes, achieved through a rare base-catalyzed strategy. We show up to 8-carbon chain walks. Congratulations Eric & Aymane on your recent Angewandte: onlinelibrary.wiley.com/doi/10.1002/an…

Thrilled to announce our incredible speaker lineup for the 2025 #ETOC Online Symposium! 📢 Join us on April 9-10 from 15:00 to 19:00 (CET).🗓️ Secure your spot today by signing up through the link below! Don't miss this exciting event! uva-live.zoom.us/webinar/regist… (1/4)

After somewhat of a hiatus, I’m back to post some recent developments for the group: First up this week, our study on the catalytic dihalogenation of allenes is now online– kudos to the team for all their hard work! pubs.acs.org/doi/abs/10.102…

I've been experimenting with the OMol25 models from FAIR Chemistry, and I'm quite happy so far. Here's a challenging system that I worked on with Buchwald Group: Pd-catalyzed C–F reductive elimination. The model gives ∆E‡ ~= 23.2 kcal/mol, vs. a reported ∆G‡ of 20.6!

🎉 Proud moment! Our Main Group team just published their 2nd paper in JACS Au! They uncovered how O₂ activation mechanisms differ across P, Sb, and Bi - pushing the boundaries of main group chemistry 🧪 Read more: pubs.acs.org/doi/10.1021/ja…

Weak coordination is very powerful with the help from bifunctional ligands; making secondary alkyl-fluoride building blocks from diverse simple substrates is highly valuable in drug discovery: pubs.acs.org/articlesonrequ…

⚡️Open Postdoc Position⚡️ We are hiring a postdoc in electroorganic synthesis with 3d transition metal catalysis. The position starts on September 1 or October 1. Applications are due by July 18. Please see details: choi.cbnu.ac.kr #Chempostdoc #Chemtwitter @chemjobber

PdH-Electrocatalytic Formal Conjugate Fluorination of β-Aryl-α,β-Unsaturated Amides with Mild and Safe Nucleophilic Fluorine Sources dx.doi.org/10.1021/acs.jo…

Our third project on alkene hydrofluorination is now published in JOC (J Org Chem/Org Lett )! We showcase the use of diverse nucleophilic fluorine sources for the synthesis of β-fluorinated amides. Congrats to Baeho and Dohyun! pubs.acs.org/doi/10.1021/ac…

Congrats to Yoojin and Taewan for the publication of Total Synthesis of (+)-Herpotrichones A–C | Journal of the American Chemical Society J. Am. Chem. Soc. KAIST Chemistry pubs.acs.org/doi/10.1021/ja…

Kim's research group at JBNU (sites.google.com/site/jbnusynth…) has one postdoctoral position available immediately. Primary hire will be on polymer synthesis and mechanochemistry. Strong candidates in organic synthesis are also considered. Please send CV to [email protected]