🔥The 9th Round of Easy Loan, Earn $40 Reward is in progress❗️ ⏰ Promotion Period: January 15th - Feburary 15th, 2025 👉 Register now and check more details at gate.io/campaigns/358

When #ubiquitin meets🐣 @NIDCR: check out our inspiring collaboration with @kerosuoLab, revealing how early brain, craniofacial and skin development are coordinated by a monoubiquitylation-based switch. Now out Nature Communications at rdcu.be/dhN90 Thank you to the team!

New preprint identifying shared and distinct mechanisms of inactivation of the #ubiquitin E1 enzyme #UBA1 across different diseases #VEXAS #SMA #lungcancer doi.org/10.1101/2023.1… Thanks to David Beck NYU Langone Health, Kylie Walters (she/her) and all contributors for a great collaboration!

There's still time to register for the Keystone Symposia in Ubiquitin Biology and Disease, joint with Autophagy and Disease, this December in Keystone! Organizers Ivan Đikić , Anastasia Henry , @BaehreckeLab . keysym.us/KSUbiquitin24 #KSUbiquitin24

Please join us this summer as the power of Ubiquitin Signaling converges with the power of Niagara Falls for FASEB #UBPSRC. We value DEIA, are raising $ for travel awards, have fantastic speakers and are excited to select new speakers from abstracts. Joazeiro Lab

We're excited with our line up of speakers for the FASEB #Ubiquitin meeting in June 2024! Join us in Niagara Falls to hear stories ranging from ubiquitin signaling and mechanisms to #RQC and targeted protein degradation (#TPD #protacs #molecularglues)

With a fixed typo, I re-invite you to come chat Ub & Targeted Protein Degradation with our welcoming community at the FASEB #UBPSRC where full days of exciting science with joyful interactions will be capped by nightly fireworks over the natural wonder of Niagara Falls.

Online Now: hRpn13 shapes the proteome and transcriptome through epigenetic factors HDAC8, PADI4, and transcription factor NF-κB p50 dlvr.it/T0chcL

New news led by Vasty Osei Amponsa: proteasome tissue variance by Rpn13 interaction with PADI4 & Rpn13 regulation of gene expression and cytoskeleton. Congrats to the team incl Monika chandravanshi, Xiuxiu Lu & thanks to Molecular Cell & @NCIResearchCtr authors.elsevier.com/a/1iJ-B3vVUPNz…

How do different mutations in #UBA1 cause autoinflammatory #VEXAS syndrome, spinal muscular atrophy #SMA, or lung cancer in never smokers #LCINS? Check out our new study with David Beck @NYU, Kylie Walters (she/her) and @NadineSamaraLab now online at The EMBO Journal doi.org/10.1038/s44318…

Thrilled to share that we teamed up across National Cancer Institute and NIH NHLBI to discover #degraders against #hRpn13 that trigger #apoptosis in #cancer cells in a study led by Xiuxiu Lu with structural data from Monika chandravanshi. 🎉 link.springer.com/10.1038/s41467…

Xiuxiu Lu at Kylie Walters (she/her) lab @NCIResearchCtr NIH and colleagues the authors identify a small molecule degrader (XL44) for hRpn13 and solve the XL44-hRpn13 structure >nature.com/articles/s4146…

Abstracts due 4/14. Join Kylie Walters (she/her), Joazeiro Lab, & Yue Xiong, PhD for this year's #UBPSRC conference, a pivotal gathering for pioneers in #Ubiquitin research. Topics incl. UBLs, chains, and compartmentalization &UB/UBL biology. More info: hubs.ly/Q02qM8jG0

Have you registered for our Ubiquitin and Ub-like Proteins conference yet? Register on or before April 28 and save $150 on registration! Join organizers Kylie Walters (she/her), Joazeiro Lab, and Yue Xiong, PhD, in Niagara. #UBPSRC Save your space: hubs.ly/Q02t1rgd0

Thank you The EMBO Journal for highlighting our work characterizing pathogenic #UBA1 mutations on the cover of the latest issue! Great collaboration with David Beck @NYU, Kylie Walters (she/her) and @NadineSamaraLab #ubiquitin #VEXAS #SMA #LCINS

Early bird registration deadline for #EMBOubiquitin2024 soon. Join us in beautiful Croatia to explore the latest in #ubiquitin biology 📅 Sep29-Oct 3, 2024. Travel awards & short talk opportunities for ECRs. Register now: meetings.embo.org/event/24-ubiqu…

NMR enthusiasts interested in managing a biomolecular NMR facility: please consider applying your NMR talent to our NCI mission to beat cancer!! linkedin.com/jobs/view/3938…

Kylie Walters (she/her) Come be part of our exciting mixed-methods structural biology environment!

Impressive developments in the #Ubiquitin and #TPD fields presented at the FASEB conference #UBPSRC From early morning runs along Niagara Falls to late evening discussions in bars: #Science glues us together. Thx to organisers Kylie Walters (she/her), Joazeiro Lab & Yue Xiong🙌

Finding structural motifs hidden within intrinsic disorder - Kylie Walters (she/her) @NCIResearchCtr Varvara Folimonova oncodaily.com/insight/135240 #Cancer #CARTCell #NCI #CancerResearch #NMR #OncoDaily #Oncology

What a fantastic meeting with impressive presentations by vibrant scientists in a beautiful location. Thank you Yifat Merbl lab and team for bringing us all together. #EMBOubiquitin24 🤩🤩🙏👏