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Human brain organelles study shows dopamine neurons must work a lot harder than those in primate relatives phys.org/news/2024-11-h… via Phys.org

Dendritic Integration Symposium next Tuesday Dec 10th. Online. Free. Great speakers !

Our paper on MouseGoggles - an open-source mini VR headset for mice - just came out! Really excited about finally integrating eye-tracking into the headset. Nice working with you Hongyu_Chang! nature.com/articles/s4159… github.com/sn-lab/MouseGo…

▶️ Now playing: @AmadDiallo_19’s derby-day winner on repeat 😍 #MUFC || #PL

G6PD deficiency triggers dopamine loss and the initiation of Parkinson’s disease pathogenesis dlvr.it/THDHdp

A comprehensive longitudinal analysis of individuals with preclinical #HuntingtonsDisease identifies #biomarkers of #neurodegeneration and somatic expansion in blood DNA, detectable years before symptom onset. Mena Farag UCL Huntington’s Disease Centre @UCLIo nature.com/articles/s4159…

Coordination between ESCRT function and Rab conversion during endosome maturation Anne Spang and colleagues The Spang Lab Biozentrum, University of Basel show that early ESCRT complexes shepherd cargoes towards sites of intraluminal vesicle formation embopress.org/doi/full/10.10…

🚨📃New Wassum Lab Paper📃🚨 Jackie Gio discovered brain pathways that support agency and habit and how chronic stress disrupts them to rob of us our agency and cause us to form rigid habits 🧵👇 nature.com/articles/s41... Free full text: rdcu.be/eaxEv

Major breakthrough in pancreatic cancer . Funded of course by the NIH

I am thrilled to share my postdoc work from the Soohyun Lee Lab, nature.com/articles/s4158…. Huge thanks to the awesome PI Soohyun Lee and collaborators Yuan Zhao, Ka Chun Lam, Francisco Pereira, and Charles R Gerfen.

NIH Brain Initiative funded multiple studies on closed loop brain stimulation for a number of neuro/pscyh conditions including Parkinson Disease. Now FDA approval granted for device that adjusts stimulation based on a person's neural activity. medpagetoday.com/neurology/park…

Science Matters. 🧪🔬🚀 I am alive because of science. We all benefit from science — every day. Science is in our homes, our hospitals, our streets, our work. For 80 years, science and technology have been a north star for the United States. In 1945, Vannevar Bush’s report to

How much analgesia is needed to manage pain levels in mice after brain surgeries? A single dose of meloxicam seems to be enough. Even the addition of opioids cannot provide a clear benefit (in line with recent work from others, see refs in our preprint): biorxiv.org/content/10.110…

Secreted neurofilament light chain after neuronal damage induces myeloid cell activation and neuroinflammation dlvr.it/TJSDtv

Proud to have contributed to JiaxuanQi's masterpiece out nature! She shows dopamine transients track the quality of song during juvenile song learning and that dopamine release is driven not just by VTA firing, but by a local cholinergic mechanism! nature.com/articles/s4158…

Striatal cholinergic interneurons act at nAChRs to depress #dopamine release, supporting an inverse scaling of dopamine release according to cholinergic activity nature.com/articles/s4159…

The latest work from the Lammel lab is out today in nature! Discover how changes in neurotensin signaling from the NAc Lat to the VTA lead to food devaluation in a mouse model of obesity 🧀🐭 nature.com/articles/s4158…

Thank you so much to Jackie Birnbaum and munib hasnain for presenting their recent paper today at CMU Biological Sciences @cmuneurosci Exciting approach to understand how to explain neural data and movement nature.com/articles/s4159…

Congrats to Kim Reinhold, soon to launch her own group in the Eaton Peabody Labs, on this labor of love. Basically, she shows that the visually recipient zone of the striatum mediates outcome-dependent trial to trial updates of behavior. nature.com/articles/s4158…

Online now: The cell-surface shared proteome of astrocytes and neurons and the molecular foundations of their multicellular interactions dlvr.it/TLHH0C