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Our latest paper is out now in PNASNews! Quantitative super-resolution microscopy of pathological aggregates reveals distinct toxicity profiles in different synucleinopathies Fantastic effort from Mike Morten Liina Sirvio @yeyu_nj and collaborators! pnas.org/doi/10.1073/pn…

A new study led by Dr Yu Ye (The Ye Lab) found that small, aggregated proteins enter cells & cause distinct toxic effects in Parkinson’s & dementia with Lewy bodies Both involve the same protein (alpha-synuclein), but it behaves differently in each disease👉buff.ly/3F4ZnjI

#ICYMI: A study led by Dr Yu Ye (The Ye Lab) found that small aggregated proteins cause distinct toxic effects in Parkinsons & dementia with Lewy bodies Both involve the same protein (alpha-synuclein) but surprisingly, it behaves differently in each disease👉buff.ly/3F4ZnjI

Come see our posters tomorrow at #connectome2022! Poster #139 with Liina Sirvio at poster session 2 and poster #197 with Mike Morten at poster session 3!

We've had a fantastic time presenting our work at #connectome2022! Thank you UK Dementia Research Institute and all attendees for three days of great talks and excellent discussion!

We had a great time at UK Dementia Research Institute #connectome2022 last week, capped off by a humble acceptance of the UKDRI Publication Prize by our very own Mike Morten! If you've not yet had a chance to read this paper you can find it here: pnas.org/doi/10.1073/pn…

We are delighted to welcome the newest member of the Ye lab, Georgie Lines! Georgie has just finished her PhD from the wonderful Wray Lab and will continue her work with iPSCs to study how protein aggregates are processed by cellular degradation mechanisms!

We were thrilled to host Professor Sir Dave Klenerman last week at Imperial Department of Brain Sciences for a wonderful talk on detecting and imaging protein aggregates in neurodegenerative diseases! Thank you Dave for your fantastic presentation and stimulating such interesting discussion!

Our wonderful postdoc Mike Morten was featured in the Imperial Department of Brain Sciences staff blog! You can read it here: blogs.imperial.ac.uk/dobs-staff/202…

We have a postdoc position Imperial Department of Brain Sciences to work on degradation of tau aggregates for up to three years, funded by a generous major projects grant Research at ARUK. Please recommend, spread the word and apply! imperial.ac.uk/jobs/descripti…

We seek a number of postdocs/technician to examine protein aggregates in neurons. Join us to build your own research career and let us support you in your personal development in the lab! tinyurl.com/MED04368 tinyurl.com/MED04501 tinyurl.com/MED04509

We're hiring a PDRA to investigate aggregates in iPSC-derived neurons and post-mortem donor samples using super-resolution fluorescence imaging and biochemical techniques! Find more information here: imperial.ac.uk/jobs/search-jo… Closing date for applications 02/08/24 #Imperial #UKDRI

We're also hiring a PDRA to explore the role of proteasomes in the clearance of toxic protein aggregates using super-resolution fluorescence imaging and biochemical techniques! Find more information here: imperial.ac.uk/jobs/search-jo… #Imperial #dementia

We have some exciting news to share from the Ye Lab! The first PhD student of the Ye Lab, Liina Sirvio, recently passed her PhD viva at Imperial College London! 🎉A big thanks to the excellent examiners Ed Tate and Catherine Lindon

There's still time to register for The Structural Frontiers of Neuroscience two day joint workshop on 19-20 November! This event will be jointly hosted by Imperial College London, UK Dementia Research Institute, and the Rosalind Franklin Institute. Find the speakers and registration link here: imperial.ac.uk/dementia-resea…

We are recruiting for two new postdocs to investigate the degradation of protein aggregates in iPSC neurons with us Imperial Department of Brain Sciences . Closing date is Nov 3 and you can find more information here: imperial.ac.uk/jobs/search-jo…

We're recruiting a PhD student to study protein aggregates in neurons using advanced fluorescence imaging techniques! Contact us if you have a background in biophysics/bioengineering/etc with prior experience in image analysis/coding. Find out more here: findaphd.com/phds/project/d…