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Check out ADAPT-MS: our flexible, scalable diagnostic framework that transforms discovery plasma proteomics directly into clinical decisions. Dynamic retraining enables single-sample diagnostics for any task - no imputation or fixed panels needed. doi.org/10.1101/2025.0…

To bead or not to bead? We evaluate five plasma proteomics workflows, finding bead-based methods enhance detection but show high susceptibility to cellular contamination bias. Strategies to optimize biomarker discovery in plasma proteomics. doi.org/10.1101/2025.0…

Heading to #ASMS2025? Our team will be there showcasing our latest breakthroughs in mass spectrometry! Don't miss the chance to connect with Matthias Mann Lab team members and discover the cutting-edge work we have been developing.

New approach tackles studying rare pediatric diseases! We developed an ontology-guided clustering framework using SNOMED CT to analyze proteomes from 1,140 children across 394 conditions - enabling meaningful insights even with tiny patient numbers! embopress.org/doi/full/10.10…

Huge congrats to atul deshmukh and team on this Cell paper! Cutting-edge MS-based proteomics across >120 individuals shows fasting muscle proteome predicts insulin sensitivity & reveals selective resistance patterns. New perspective for diabetes medicine!

Nano-scale, mega-impact: nanoPhos delivers 100× phosphoproteomics sensitivity, 70k sites from 1µg, 8k from 10ng! Powered by SPEC, it enables phosphoDVP: deep spatial phosphoproteomics from 1000 neurons, hitting 17k sites, a game changer for spatial omics. biorxiv.org/content/10.110…

Protein digestion in 200 nL on solid-phase tips: SPEC enables low-input proteomics—even with SDS/SDC at high levels. From FFPE and muscle to high throughput plasma. SPEC is a universal and Evosep-compatible protocol. biorxiv.org/content/10.110…

Don't forget to check out Marvin Thielert's poster 773 on single cell proteomics at #ASMS2025! #SingleCellProteomics

Don't forget to connect with our team members at #ASMS2025. Talks and poster line-up below 👇

Congratulations Vincent Vincent Albrecht - well done!