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62yo w/ Gleason 6 PCa after TURP. PSA 3,5 mpMR: PIRADS 2 PSMA-PET: 2 focal uptake in central zone (CZ) of prostate. TRUS Bx: negative ☢️Teaching point: physiological CZ PSMA uptake (Mickey Mouse ears sign) ✅symmetrical and low uptake ➡️ not commonly seen (pitfall)

CASE 1: 22 YO male pt w/ dizziness and headache; 🔍MRI: Lesions in splenium of corpus callosum, bilateral frontoparietal & centrum semioval w/ ↑signal on T2wi/FLAIR, ↓signal on T1wi & restricted diffusion on DWI w/ mild peripheral contrast enhancement. PET shown in the picture.

CASE 2: 68 YO female pt w/ memory deficit, confusion & gait disturbance; 🔍MRI: Lesion in splenium of corpus callosum w/ ↑signal on T2wi/FLAIR, ↓signal on T1wi & restricted diffusion on DWI w/ intense contrast enhancement, surrounded by vasogenic edema. PET shown.

Diagnosis?

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24yo Male, 3w of fever and visceral crisis 🔬Burkitt Lymphoma ☢️Staging PET w/ massive bone, nodal and visceral disease. ☠️no brain uptake ☣️Complete metabolic response Striking images showing cancer “cure”! OncoHematology often brings drops of good news through our reports.

55yo Male w/ pleural recurrence of a lung adenoca ALK+. ☢️See the beauty of ALK targeted therapy evolution and its objective response through metabolic images. Maurício Ribeiro, MD João Alessi, MD Karina Sacardo Andrea Shimada Bruna Zucchetti Fernando Santini IASLC HSL MedOnc Fellows

58yo Fem, assymptomatic, metastic melanoma treated w/ anti-PD1 Nivolumab. FDG-PET/CT ➡️ extensive pneumonitis w/ intense uptake (immune related adverse event) ✅Diffuse alveolar damage pattern - GGO + septal thickening (worse clinical outcome) International Cancer Imaging Society Society for Immunotherapy of Cancer Journal for ImmunoTherapy of Cancer

Anwar Padhani prof. Stefano Fanti silke gillessen @morr316 Christopher Sweeney, MBBS New data showing that almost 1/4 of CRPC pts w/ 2nd gen ADT can progress without PSA PD. Such pts have worse prognosis. Maybe it’s time to study advanced imaging assessment in such scenario in order to intensify / change management. PSMA can have an interesting role in CRPC!

79yo F w/ weight loss and liver nodules. ☢️ PET/CT - lung, liver, spleen, adrenal and kidney metabolic hypovascular lesions 🔬Tuberculosis 📝 FDG-PET is a good method for therapy assessment in chronic inflammatory / infectious disease SNMMI @officialEANM

Reassessing Patterns of Response to #Immunotherapy with #PET: From Morphology to Metabolism doi.org/10.1148/rg.202… In this RadioGraphics article Larissa Bastos et. al. comprehensively reviewed the response assessment criteria for immune checkpoint inhibitors with PET #RGphx

Combined with morphologic criteria, PET can play an essential role in assessing response to immune checkpoint inhibitor therapy and adverse events during immunotherapy as one of the main treatments for cancer. bit.ly/3bHJy3Q #RadRes #RadEd Larissa Bastos

Happy to share the newest publication from our group, in which I had the opportunity to collaborate w/ colleagues & friends. Grateful for the opportunity to write about such a relevant topic today. bit.ly/3fuM5zZ

📌 Coordenado pelo Prof. Dr. Carlos Alberto Buchpiguel e Dr. Marcelo Queiroz, o Curso Hands On de PET PSMA será realizado presencialmente no InRadiando nos dias 29 e 30 de outubro. Acesse e faça a sua inscrição: bit.ly/HandsOnPETPSMA.

📢 Great news! Our team Felipe de Galiza Larissa Bastos Marcelo Queiroz Carlos Buchpiguel is humbled to have 4 of our papers recognized as top reads for radiology residents. 📚 Grateful for the opportunity to contribute to the field and support future radiologists. pubs.rsna.org/radiographics/…

Happy to share this recent published review w/ Larissa Bastos RENATA MOREIRA #priromano authors.elsevier.com/a/1hd%7E%7E7iQ… Thanks Andrei Purysko NickSchieda for the kind invitation to join this great group. #FOAMrad #radres