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retroperitoneal mass core biopsy from a middle-aged M thoughts?

Not all tumors that produce Calcitonin is Medullary Thyroid Carcinoma Laryngeal Neuroendocrine Tumors ALSO produce/stain with Calcitonin. If unsure, get serum 🩸 🧪 Calcitonin; more likely ⬆️ in Medullary #pathx #pathology #headandneck #ops #entpath #pathtwitter

Check out our June edition packed with a range of practical articles for the general and specialist pathologist. onlinelibrary.wiley.com/toc/13652559/2…

🚨Check out our new publication: The Spectrum of Vascular Lesions of the Upper Female Genital Tract: A Report of 55 Cases Kyle Devins, MD Mass General Brigham Pathology MGH Pathology International Journal of Gynecological Pathology #GYNpath #BSTpath journals.lww.com/intjgynpatholo…

✨️Eosinophilic esophagitis Major criteria:≥15 eosinophils/HPF (40x magnification) in the squamous mucosa Minor criteria: -Eosinophils concentrated in the surface epithelium -Basal zone hyperplasia -Eosinophilic microabscesses -Eosinophil degranulation -Surface desquamation

#ポケモン版深夜の真剣お絵描き60分一本勝負 ゾロア（ヒスイのすがた）です。

He vuelto a dibujar celulitas 💟 🔬Sarcoma sinovial / Synovial sarcoma🔬 #pathology #BSTpath #PathTwitter

🩵Chordoma / Cordoma 💙 🤕Malignant tumor with notochordal differentiation 📍Skull, vertebrae, sacrum, coccix 🔬Nests and cords, physaliphorous cells 🫧 IHQ: CK, S100, brachyury #path #pathology #BSTpath #PathTwitter #medicine

Type I stomach NET -More common in the gastric body -often multifocal -usually <2cm 🔬Arranged in nests,cords or trabeculae 🔬Bland,round cells with salt & pepper chromatin & amphophilic cytoplasm 🔬background oxyntic mucosa is atrophic with metaplasia with ECL cell hyperplasia

まったく、あんたって子は……

🌊 Extraskeletal myxoid chondrosarcoma 🌊 - Rare sarcoma (<1% ) - Proximal extremities and limb girdles - Cords and nests of interconected cells - Myxoid/chondromyxoid matrix - IHQ: INSM1, NSE, synaptophysin, S100, c-kit - NR4A3 rearrangement #pathology #BSTpath #pathTwitter

Alveolar soft part sarcoma (ASPS), nested, epithelioid cells with granular/clear cytoplasm. Rich vascular network. IHC: TFE-3 #ISBSTP #BSTPATH

La microangiopatia trombotica tiene muchas etiologias. Hallazgos clasicos in lien mesangiolisis, trombos de fibrina, fragmentos eritrocitarios, y arteriolitis necrotizante.

I give you the IHC 🎨: SMA You tell me what cell it is ⬇️ #pathx #pathologyx #ihc #pathtwitter #bstpath

B Cell Maturation Stages Easy to Remember Flow Chart #medicine #hematology #medtwitter #blooducation

Spindle cell lipoma: ▫️Benign neoplasm ▫️Middle aged to elderly men ▫️80% arise in the subcutaneous tissue of the neck (posterior), back and shoulders ▫️Mature adipocytes + bland spindle cells + rope-like collagen fibers ▫️Myxoid stroma with mast cells #DermPath #BSTPath

Not always easy to recognise #FlatEpithelialAtypia, but hope this composite image may help. On ⬅️ columnar cell change (elongated bland nuclei). On ➡️ FEA - smooth contour, >1 layer, low grade round nuclei (like LGDCIS), not perpendicular to basement membrane. #pathology

The remaining #Wallhangers . . . these pertain to tumor with "pink cells." (2/2)

Oral epithelial dysplasia WHO-2022: 3-tiered grading system Defining dysplasia grade only in this manner oversimplifies the complexity of grading Cytological atypia confined to the basal third may be sufficient for a diagnosis of severe dysplasia, depending on individual

Proposed decision algorithm for diagnosis of uterine smooth muscle neoplasms with atypical features 94% of LMS showed ≥ 1 genomic alteration involving TP53, RB1, ATRX, PTEN, CDKN2A, or MDM2, with 80% showing alterations in ≥ 2 of these genes. Two or more abnormal IHC results