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Our latest preprint: The much awaited structures of human muscle glycogen synthase, revealed in full glory at 3-4 A by cryo-EM. Nice work from our own Norvey. Big shout-out to fab collaborators Pfizer Inc. rare disease unit, and former colleagues Centre for Medicines Discovery biorxiv.org/content/10.110…

Plugging also the highly impressive and complementary work from ergiola Zeqiraj & Laura Marr - a field day for glycogen biosynthesis! biorxiv.org/content/10.110…

Glad to have been a part of this fascinating project! Preprint from ergiola Zeqiraj & Laura Marr deciphering structure & function of phosphorylated GS-GN complex. Another great collaboration between the two labs Kei Sakamoto Sakamoto Lab #GlycogenBiology biorxiv.org/content/10.110…

Our pre-print is out! New insights into glycogen synthase regulation and glycogen biosynthesis. Big thanks to everyone involved! Check it out biorxiv.org/content/10.110…

Happy to share our new preprint proving mechanistic insights how glycogen synthesis is regulated via phosphorylation and interaction with glycogenin! Work led by ergiola Zeqiraj and Laura Marr Understanding Life in Molecular Detail and nice contribution by Dipsikha Biswas 🇵🇸🇺🇦🌻 Sakamoto Lab

Take a look at our new article out in Structure. We used ESEEM, HDX-MS, and MD to examine the link between pocket modification and mechanical tension activation of MscL. cell.com/structure/full… Pliotas Group Anton Calabrese Kalli Group 🧫➡️💻➡️📊 Frank Sobott FBS Research Facilities Leeds Integrative Membrane Biology

Great to see this out! Thank you to everyone involved

Here, researchers describe the structural basis of glycogen synthase inactivation by phosphorylation. ergiola Zeqiraj Sakamoto Lab and @Astbury_BSL go.nature.com/3yf2JvD

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