They’re just the greatest!

Lab’s first pre-print! We found that loss of EF-P and the ABCF-family ATPase YfmR is lethal to B. subtilis due to translation failures during early elongation. Great work Hye-Rim Hong, Cassidy Prince and Dennis Wu! #ribosomes biorxiv.org/content/10.110…

Out now in PNASNews we used Tn-seq to identify genetic interactions with EF-P in B. subtilis. We found that 1) the ABCF YfmR (Uup) is required in absence of EF-P in some conditions pnas.org/doi/10.1073/pn…

YebC2 resolves ribosome stalling at polyprolines independent of EF-P and the ABCF ATPase YfmR biorxiv.org/cgi/content/sh… #biorxiv_micrbio

Our timely contribution to the growing body of YebC2/TACO1 literature 🤩! YebC2 is a third factor that prevents ribosome stalling at prolines. Associates with 70S and important for fitness in absence of EF-P and YfmR. biorxiv.org/content/10.110…