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By using a timer protein, which changes color from blue to red, @m_ono_r and colleagues create a new tool capable of capturing rapid changes in behavior and development of immune cells in the body bit.ly/2tCaHP0 @AlinaPads @MoDucker @BendingLab

Drosophila immune cells extravasate from vessels to wounds using Tre1 GPCR and Rho signaling bit.ly/2Kq8Rae

Adult Drosophila have an open cardiovascular system. However, Thuma et al. find that in late pupation, hemolymph flows through Drosophila wing veins, providing a unique opportunity to investigate mechanisms driving immune cells to extravasate bit.ly/2Kq8Rae

ICYMI multi-view light-sheet microscopy revealed embryogenesis of the crustacean Parhyale hawaiensis doi.org/10.7554/eLife.…

Our paper on cellular mechanism of large-scale curvature sensing is out 😃 #@NaturePhysics by Chen et al. nature.com/articles/s4156…

Sidney Brenner's thoughts on science, success, and skewed incentives kingsreview.co.uk/articles/how-a…

Our "scary" observation that SMIFH2 is a somewhat potent inhibitor of Myosin family is on bioarchive. A big caveat when using this drug. The Formin Inhibitor, SMIFH2, Inhibits Members of the Myosin Superfamily biorxiv.org/content/10.110…

There's growing evidence that SARS-CoV-2 might cause the body to generate antibodies that attack its own tissues, perhaps explaining why some get so sick or for so long. #LongCovid go.nature.com/3941i83

Long under-appreciated, fibroblast biology is a key aspect of understanding how the immune system responds to tumours and may hold the key to improving immunotherapy in this tricky space elifesciences.org/articles/57243…

.Margot Riggi and I are excited to release "Phase Separation 101," a visual resource for undergrad teaching. Check it out here: animationlab.utah.edu/phase-separati… and many thanks to the researchers and educators who gave us their invaluable feedback! A short preview below:

Here is a Share Link to our recent review Trends Cell Biology focusing on Novel imaging methods and force probes for molecular mechanobiology of cytoskeleton and adhesion. Nice to share beautiful studies from wonderful labs. authors.elsevier.com/a/1fg8M3QxxSnJ…

People are asking me about the origins of and key milestones in the timeline of #bioorthogonal chemistry, so here is a quick summary. 1/n

Our new Current Opinion in Cell Biology review article “Single molecule imaging unveils cellular architecture, dynamics and mechanobiology” is now freely available online for a limited time with this link: authors.elsevier.com/c/1j5we3PA3sYq… Giannone Lab

Actin-driven nanotopography promotes stable integrin adhesion formation in developing tissue. doi.org/10.1038/s41467…

Excited to share our new paper "Actin-driven nanotopography promotes stable integrin adhesion formation in developing tissue". rdcu.be/dWie7 We study the single molecule dynamics of integrin adhesion proteins in developing Drosophila embryonic muscle attachment.

Our work on a new technique we call 3D micropatterned traction force microscopy (3D-μTFM) is now out: onlinelibrary.wiley.com/doi/full/10.10…

Looking to dive into #MachineLearning? I’m sharing my entire university course online—completely free! Each lecture is recorded and connected to hands-on demonstration workflows and interactive dashboards, so you can follow along at your own pace. I’m excited to help you learn!

Correlative two color 3D super-resolution single molecule localization microscopy and block face electron microscopy of mitochondria and the endoplasmic reticulum in vitreously frozen COS-7 cells doi.org/10.1126/scienc…

Incredibly excited that our paper linking single molecule states of TF binding to gene expression using quantitative thermodynamic models is out in Nature today. An amazing collaboration with the Bintu Lab. Congrats to Ben, Michaela, and Julia! nature.com/articles/s4158…

Today, in a paper in Science, we resolve a long-standing heated debate on what powers the organization of the DNA in our cells: We show by real-time movies that a single condensin protein complex extrudes loops of DNA! science.sciencemag.org/content/early/…