Lingyin Li, PhD (@li_lingyin) 's Twitter Profile
Lingyin Li, PhD

@li_lingyin

Prof. at @stanford.edu & Core Investigator at @arcinstitute.org | Uncovering drug targets and therapeutics in innate immunity and for cancer and autoimmunity

ID: 1600954581155909632

linkhttp://arcinstitute.org/labs/lilab calendar_today08-12-2022 20:45:10

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Patrick Hsu (@pdhsu) 's Twitter Profile Photo

More ML advances from Arc Institute 🔥 Hani Goodarzi's lab reports in Cell Genomics a machine learning model that predicts RNA secretion. This will enable cool applications in noninvasive diagnostics and synthetic biology!

More ML advances from <a href="/arcinstitute/">Arc Institute</a> 🔥

<a href="/genophoria/">Hani Goodarzi</a>'s lab reports in <a href="/CellGenomics/">Cell Genomics</a> a machine learning model that predicts RNA secretion. This will enable cool applications in noninvasive diagnostics and synthetic biology!
Lingyin Li, PhD (@li_lingyin) 's Twitter Profile Photo

It is a great honor to participate in Cell Chemical biology’s special issue focusing on Inflammasomes and Immunoregulation to celebrate the 30th anniversary of the journal in 2024. Also celebrating 10 years of ENPP1 and extracellular cGAMP. authors.elsevier.com/a/1j3578jWWJxL…

Arc Institute (@arcinstitute) 's Twitter Profile Photo

⚡After discovering the role of the ENPP1 enzyme in masking cancer from the immune system, Lingyin Li Lab has found a new enzyme, ENPP3, that also inhibits cGAMP-STING signal + anti-tumor immune response, preventing immunotherapies like Keytruda from working effectively. 🧵⬇️

⚡After discovering the role of the ENPP1 enzyme in masking cancer from the immune system, <a href="/Lingyin_Lab/">Lingyin Li Lab</a> has found a new enzyme, ENPP3, that also inhibits cGAMP-STING signal + anti-tumor immune response, preventing immunotherapies like Keytruda from working effectively. 
🧵⬇️
Arc Institute (@arcinstitute) 's Twitter Profile Photo

An exciting update from Arc! Today, we launched our Scientific Advisory board and welcomed our first Scientific Advisors, Nobel Laureate Dr. Carolyn Bertozzi and Dr. Aviv Regev, EVP of Genentech Research & Early Development. Both Drs. Bertozzi and Regev have long careers

An exciting update from Arc!

Today, we launched our Scientific Advisory board and welcomed our first Scientific Advisors, Nobel Laureate Dr. <a href="/CarolynBertozzi/">Carolyn Bertozzi</a>  and Dr. Aviv Regev, EVP of Genentech Research &amp; Early Development.

Both Drs. Bertozzi and Regev have long careers
Lingyin Li, PhD (@li_lingyin) 's Twitter Profile Photo

Congratulations to Zhijian "James" Chen for winning the #Lasker2024 for his foundational discovery of cGAS! laskerfoundation.org/winners/cgas-e…

Lingyin Li, PhD (@li_lingyin) 's Twitter Profile Photo

This is certainly not the first cGAMP transporter, but the insight reported here might be the last missing piece to realize the full potential of STING agonists for cancer immunotherapy which started from DMXAA.

Lingyin Li, PhD (@li_lingyin) 's Twitter Profile Photo

It would have been very nice to recognize Debora Marks's conceptual advances in protein structure prediction and design alongside David, who absolutely deserves all the recognition as well! She would have a great story to tell in Stockholm.