🔥The 9th Round of Easy Loan, Earn $40 Reward is in progress❗️ ⏰ Promotion Period: January 15th - Feburary 15th, 2025 👉 Register now and check more details at gate.io/campaigns/358

Let’s dream a bit. How would you dramatically reorg biotech research / drug development to make dramatically faster progress towards curative therapies? (Don’t say “use AI”, hypothesis/candidate generation under current structure isn’t a bottleneck)

After over a year of incubating, I’m excited to share a new project inspired by a ~decade of in vivo drug discovery experience 🧬 Artemis is a Focused Research Organization (FRO) to establish alternative, naturally physiologically human-like animal species for complex disease

The time of day that immunotherapy is given seems to really, really matter. Why? note: a recent randomized study (quote given blow) presented at a major cancer conference found that giving immunotherapy in the morning instead of the evening led to a 2x higher survival rate.

does anyone know of a cool biotech/bio-ml startup should i write about? something that has a fun fix of - is doing something very unique and valuable but… -it is hard to understand why it is unique or valuable i havent covered one in 5~ months and im getting antsy about it

I would extend this to applied ML/AI as well. Less focus on bean counting papers & glam status of journals & more focus on making datasets, tools, methods, analyses that have long-lasting real impact on the fields that we work in.

Science writing from the last two years that stuck with me: (1/many)

Really pleased to share what I have been working on for 2 months: 🇬🇧 UK SovAI are today announcing our £8m seed investment into OpenBind - A consortium that will actually make AI for drug discovery great by generating 500k experiment protein-ligand complexes!! Explainer 🧵 (1/n)

📢 We just released our complete playbook for thesis-driven philanthropic funds. A new model that's creating better outcomes for donors, scientists, and society. Here's how it works: 👇

LAUNCH DAY 🚀 Today I’m launching a new podcast, Hard Drugs, with Jacob Trefethen (Jacob Trefethen) Our first episode is about lenacapavir — a new HIV drug that blocks infections with an efficacy rate of nearly 100%, and which could completely change the fight against HIV worldwide.

🚀 Xaira Therapeutics has just dropped a game-changer for AI-driven biology. Today, we unveiled X-Atlas/Orion, the largest publicly available genome-wide Perturb-seq dataset to date—spanning 8.4 million single cells with perturbations across all ~20,000 human protein-coding

🚨 (1/2) Align × ATCC are partnering to build the world’s largest public microbial phenotyping dataset. ✅ 1K strains ✅ 1K conditions ✅ 1M reproducible experiments ✅ Open access Built using high-throughput automation and linked to ATCC’s authenticated genomes,

Most advice on fundraising comes from VCs, and is written for software companies. We’ve published one that’s a little different. By @andreacoravos & Rachel Katz, who have successfully fundraised for and exited their own companies, here’s a guide for founders in healthcare and

Sara Mostafavi (Genentech ) & I (Stanford University) r excited to announce co-advised postdoc positions for candidates with deep expertise in ML for bio (especially sequence to function models, causal perturbational models & single cell models). See details below. Pls RT 1/

What does it take to fund a more abundant future? Our new Head of Strategic Investments, Eli Dourado, lays out a clear framework rooted in technoeconomics, sociopolitics, and entrepreneurship Read his perspective: asterainstitute.substack.com/p/how-we-get-t…

The Arc Institute Virtual Cell Challenge: prizes worth up to $100,000 for accurately predicting cellular responses to genetic or chemical perturbations.

How concerned should we be about AIxBio? We surveyed 46 bio experts and 22 superforecasters: If LLMs do very well on a virology eval, human-caused epidemics could increase 2-5x. Most thought this was >5yrs away. In fact, the threshold was hit just *months* after the survey. 🧵

We’re opening the waitlist to the first 50 signups! Gaia is evolving: 💡 New capabilities ✨ Improved UI/UX 🧬 Beyond single sequence search Help shape the future of biological data. Join the waitlist 👉 shorturl.at/dKae4 Let’s build this together.

1/4 🚀 Announcing the 2025 Protein Engineering Tournament. This year’s challenge: design PETase enzymes, which degrade the type of plastic in bottles. Can AI-guided protein design help solve the climate crisis? Let’s find out! ⬇️ #AIforBiology #ClimateTech #ProteinEngineering

By this time next year, either: 🏆 we'll have engineered PETase enzymes actually work industrially & recycle plastic ... or we'll know that AI-for-proteins is still a bit underbaked 😜 Excited to see what happens!!!! 😬 Spread the word ⬇️

I just released an essay series on a topic I've been thinking about, on and off, for a few years: What does AI progress mean for medical progress? Many people working on AI dream it will help cure cancer and prevent disease. I wanted to create a more specific roadmap: