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Center for Cell Plasticity and Organ Design congratulates CPOD Members Sundeep Kalantry & Longhua Guo on their prestigious NIH awards! Read more about their research & NIH awards written by Kelly Malcom of The University Record: record.umich.edu/articles/three… #GoBlueMed

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Excited to share our work on live imaging of the entire course of body regeneration in the marine flatworm Macrostomum using transgenics & advanced microscopy. We hope these tools can unlock the unique biology of this fascinating intertidal animal. cell.com/cell-reports/f…

Introducing 2024 AFAR Grants for Junior Faculty recipient Yang Lyu of Rutgers University who will research “Motivation Reward and Longevity as Influenced by Serotonin Dopamine and Metabolism.” Learn more here: afar.org/grantee-profil… #Longevity #Protein #Metabolism

There are good, bad, and ugly Professors. This is ugly.

Online now! Dai et al. report age-associated physiological and molecular changes in the sexual lineage of S. mediterranea, and global reversal of such changes after regeneration. Longhua Guo Xiaoting Dai JK Nandakumar lab AFAR Pew Health Center for Cell Plasticity and Organ Design doi.org/10.1038/s43587…

Planarian worms do not lose adult stem cells with age and can regenerate into a more youthful version of themselves, according to a new study by Xiaoting Dai, Longhua Guo University of Michigan & Vadim N. Gladyshev Gladyshev Lab et al. #aging doi.org/10.1038/s43587…

Planarian worms can regenerate into a more youthful version of themselves, finds a new U-M study. Figuring out the secrets of their immortality could lead to insights about aging for mammals, including people michmed.org/AQYNm

Our work is now online at Nature Aging (nature.com/articles/s4358…), with exciting updates: comparison with mice/human aging; expanded number of samples for single cell analysis; molecular and cellular signatures of aging and rejuvenation; assay/discussion on global rejuvenation.

Research from fellow Xiaoting Dai and the Longhua Guo lab in UMPhysiology published in Nature Aging shows regeneration of lost tissues in older planarians led to reversal of these age-associated changes in tissues both proximal and distal to the injury. nature.com/articles/s4358…

Chambers et al. w/Cory Dungan, PhD Boehringer Ingelheim Prof Steve Horvath Clock Foundation UKY Center for Muscle Biology UA Exercise Science UARK Health, Human Performance and Recreation UA COEHP UArkansas Research in Aging Cell Exploring epigenetic aging, senescence, and regeneration in skeletal muscle #myotwitter onlinelibrary.wiley.com/doi/full/10.11…

C. elegans transgenerational avoidance of P. fluorescens is mediated by the Pfs1 sRNA and vab-1 | Science Advances science.org/doi/10.1126/sc…

Golden retriever picks up cat for family photo

New publication from the lab pnas . With the collaboration of Dr. Ping Kang Ping Kang, we uncovered how developmental NF-kB signaling links developmental timing (time to maturity) to lifespan😊😊pnas.org/doi/10.1073/pn…

Join #CPOD, Jason Spence & Longhua Guo tomorrow 5/20 at 4pm in Buhl 5915 for Katia Del Rio-Tsonis seminar! #GoBlueMed #UmichMedScience

Planarians made the cover. Aging and Rejuvenation in planarians: doi.org/10.1038/s43587…

Excited to share our new study in Cell—congrats to Daniel, co-authors, and our collaborators in the Peter Ly What began as pure curiosity led to a tool for modulating mitochondrial abundance in vitro and in vivo. A new direction for the Wu lab begins! cell.com/cell/fulltext/…