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Central inhibition of HDAC6 re-sensitizes leptin signaling during obesity to induce profound weight loss dlvr.it/T57GQs

Online Now: Neuroendocrine gut–brain signaling in obesity dlvr.it/T7hVVj #trends #endocrinology #metabolism

Really proud to publish this fascinating paper on receptors responsible for sexual touch. It's easy to get prudish and Victorian on this sort of work, but sexual and reproductive health is extremely important nature.com/articles/s4158…

I’m very excited to share that my graduate work is now online in Science Magazine today! With generous help from my mentor 池谷裕二 and my amazing teammates, we investigated a top-down pathway for volitional heart rate regulation! science.org/doi/10.1126/sc…

Cerebrospinal fluid links the brain and peripheral sensory system and drives headache in migraine with aura! We’re excited to share our newest article just published today in Science Magazine . Please read along: science.org/doi/10.1126/sc…

🚨❗️🚨 New Paper Alert My postdoctoral work now out in nature. We find that sensory neurons drive breast cancer metastasis via an activity-dependent paracrine signalling mechanism mediated by substance-P, extracellular ssRNA & TLR7 receptor. (1/11) urldefense.com/v3/__https://w…$ 🧵👇🏾

Now online! Divergent sensory pathways of sneezing and coughing dlvr.it/TD69TG

Here suppression of the DMV–vagus–jejunum axis controls intestinal fat absorption by shortening the length of microvilli with therapeutic potential for #weightloss nature.com/articles/s4158…

How our brain and body talk to each other, with control of inflammation and our immune response cell.com/cell/fulltext/… Cell Asya Rolls Nadine Gogolla Miranda Popescu Steve Liberles and colleagues, open-access

After a strong start, competition for Novo Nordisk Eli Lilly and Company is coming in the #weightloss space, with widespread innovation to bring options for more people @amgen Roche Altimmune, Inc. Structure Therapeutics Viking Therapeutics Pfizer Inc. Boehringer Ingelheim economist.com/business/2024/… The Economist

Our latest paper with Ari Molofsky is out! tweetorial to follow. Group 2 innate lymphoid cells promote inhibitory synapse development and social behavior | Science science.org/doi/10.1126/sc… Jerika Barron @ Nick Mroz

Using multiple techniques the authors affirm that Gfral expression is overwhelmingly restricted to the brainstem in healthy mice Molecular Metabolism Centre universitaire de santé McGill Randy J. Seeley, Ph.D. sciencedirect.com/science/articl…

Does loss of GIPR signaling sensitize GLP-1R+ neurons, enhancing the actions of GLP-1R agonists? New data from Randy J. Seeley, Ph.D. University of Michigan Molecular Metabolism UMich Diabetes Cntr sciencedirect.com/science/articl…

Now online! Characterizing and targeting glioblastoma neuron-tumor networks with retrograde tracing dlvr.it/TGdrYk

Improving appetite and weight gain in cancer/chemotherapy... jci.org/articles/view/… Xinxia Zhu & team OHSU News tested the melanocortin-4 receptor antagonist TCMCB07 in several preclinical models of chemotherapy.

Cellular crosstalk in skeletal muscle? A surprising role for mast cells? Histamine as a signal transducer during exercise? This was an amazing ride during my time TeamDerave, now published in Cell Metabolism (1/11) UGent Geneeskunde & Gezondheidswetenschappen, FWO sciencedirect.com/science/articl…

We described a neural mechanism for motion-induced hypothermia which can also be targeted to treat obesity. Congratulations to ⁦Longlong (Lucas) Tu⁩ who started this scientific journey trying to understand his own miserable suffering from motion sickness. nature.com/articles/s4225…

A personal interest in #motionSickness led them to discovering potential new options for treating #obesity. Dr. Yong Xu Longlong (Lucas) Tu explain. Nature Metabolism BCMHouston #BCMPostdoc #brainCircuit bcm.edu/news/motion-si…

Understanding of how the #brain regulates #bodyTemperature during #motionSickness may provide unconventional targets for the treatment of #obesity. Dr. Yong Xu Longlong (Lucas) Tu et al explain their findings Nature Metabolism BCMHouston #BCMPostdoc blogs.bcm.edu/2025/04/17/fro…