A semi-supervised imaging, spatial transcriptomics, and single-cell workflow uncovers transitions of PanIN progression and the surrounding microenvironment. Luciane T Kagohara 🇧🇷🧬👩🏻‍🔬👩🏻‍💻 @FertigLab cell.com/cell-systems/a…

New preprint from Luciane T Kagohara 🇧🇷🧬👩🏻‍🔬👩🏻‍💻 @FertigLab Dr. Elizabeth Jaffee Won Jin Ho Ashley Kiemen Ashi_W & colleagues Johns Hopkins Kimmel Cancer Center Convergence Institute Spatial multi-omics reveal intratumoral humoral immunity niches associated with tertiary lymphoid structures in #PancreaticCancer immunotherapy

finally out in full form - i'm excited to share our work showing the utility of adding a PDE-5 inhibitor onto vaccine (msln-listeria) to reprogram the myeloid cells in PDAC - led by the amazing Nicole Gross carter zhang, also jacob mitchell @FertigLab insight.jci.org/articles/view/…

incredible work led by Dimitri Sidiropoulos to peruse through the TLS forming in PDAC - a great show of making the most of multiple state-of-the-art tools to synthesize our understanding

Not the official Science Advances cover of this month, but you can still find it in the current issue! Check our latest paper where we used 3D-CODA to design assembloids that mimic the complexity of human fallopian tubes. Paper:science.org/doi/10.1126/sc…

Nice to see the final version of this Cancer Discovery paper. The triangles made it to the title page (IYKYK)! Mechanisms of Resistance to Oncogenic KRAS Inhibition in #PancreaticCancer aacrjournals.org/cancerdiscover…

1/8 Excited to share our latest study in Nature Immunology led by @DanielShuMD on TLS in #HCC patients treated w/ neoadj ICB: ⏩ TLS linked to improved outcomes ⏩ Novel "involuted" TLS found in tumor regression zones 🔗 nature.com/articles/s4159…

7/8 Congratulations to all authors, @DanielShuMD, now a junior faculty at UMD, co-corresponding @FertigLab, and Won Jin Ho Luciane T Kagohara 🇧🇷🧬👩🏻‍🔬👩🏻‍💻 . This paper was truly a tour-de-force...

We asked @MoffitLab, Mingyao Li, Qing Nie @uci_cmcf, Kazumasa Kanemaru, Teichlab, Daniel Dar Weizmann Institute, Luciane T Kagohara 🇧🇷🧬👩🏻‍🔬👩🏻‍💻, shalev itzkovitz, roser, Itai Yanai, @FertigLab, and Fabian Theis about the main bottlenecks facing Spatial Transcriptomics cell.com/cell-systems/a…