💫🌟Resistance to selective FGFR inhibitors in FGFR-driven urothelial cancer🌟💫 🟠 FGFR inhibitors show positive clinical data in FGFR-driven bladder cancer, but there is room for improvement in urothelial malignancies. 🟠Understanding resistance mechanisms to FGFR inhibitors is

Very excited to see our study on a case of ALL to AML switch after CAR-T treatment out in Nature Cancer! Using deep genome sequencing, we show the cancer switched cell types to escape therapy. Broad Institute Wellcome Sanger Institute Gad Getz Laboratory Thread below 🧵 nature.com/articles/s4301…

On women in science, with Magdalena Skipper, EIC nature, from the new Ground Truths podcast. It's algorithmically X-suppressed if I put in the link, which can be found in my profile

Interested in deep learning for medical imaging inverse problems at scale? Join the Biomedical Imaging group at Microsoft Research to work on this beautiful project! jobs.careers.microsoft.com/global/en/job/…

Timely detection of pre-cancer lesions can improve patient survival but is challenging due to the worsening global shortage of pathologists. Check out our latest work on how deep learning can improve screening capacity by partially automating detection of pre-cancer lesions👇👇

The AACR-AstraZeneca Career Development Award for Physician Scientists, in Honor of José Baselga, is a three-year, $300,000 grant to support projects related to the development of innovative targeted therapeutics. Apply by December 5: bit.ly/3Fjwwaq

Absolutely! Physician-scientists and scientists with parenting responsibilities 👇👇

Profound 🧡

Join a great team in Liverpool - strong record of being very friendly!! Job vacancy: Consultant Ophthalmic Pathologist, Liverpool University Hospitals NHS Foundation Trust, Liverpool | trac.jobs nhsjobs.com/job/UK/Merseys…

Thrilled to announce our collaboration with Cyted Health and Cancer Research UK to scale early detection of esophageal cancer with AI.

Very excited to share our latest preprint on somatic mutations in the normal stomach. We found many surprises, incl. hypermutant glands, recurrent somatic trisomies and a unique landscape of driver mutations. Thread below! biorxiv.org/content/10.110…

Couldn’t agree more ❤️

New article from katherlab in Nature Medicine: large language models for interoperability in healthcare 👇

Finally out in Nature Protocols : our group's workflows for end to end computational pathology. Compatible with UNI and other foundation models. Led by Omar S.M. El Nahhas from katherlab journal link: nature.com/articles/s4159… full text: rdcu.be/dT35l

Beautiful work from Jyoti Nangalia Peggy Goodell Peter Campbell and team 👏

This new paper nature today on the genesis and evolution of stomach cancer goes against the alt-model nature.com/articles/s4158… nature.com/articles/d4158…

The stomach is an organ unique in its function, environment and exposures. How does this affect the mutations that normal cells in the stomach acquire? What does this reveal about the origins of stomach cancer? These questions and more in our Nature paper: nature.com/articles/s4158…

Catch our CRUK Cambridge Centre: Breast Cancer Co-lead, Prof Jean Abraham, talking more about this research and new treatment approach on BBC Radio 4 PM from 5pm and BBC News at Six this evening. bbc.co.uk/news/articles/…

A huge thank you to all patients, all the NHS hospital trusts, and trials teams that took part in the PARTNER trial Cambridge University Hospitals NHS; CRUK Cambridge Centre: Breast Cancer; CRUK Cambridge Centre; Cambridge University; NIHR Cambridge Biomedical Research Centre Thanks to Nature Communications and their editorial team!

So proud of Jean Abraham and her team for this study that is all over the news today! Catch the BBC1 coverage of these amazing clinical trial results for patients with BRCA positive breast cancer. Thank you for all you do for patients! CRUK Cambridge Centre: Breast Cancer