
Marco Osterwalder
@m_osterwalder
Cardiac development and functional genomics @DBMR_UniBe
ID: 2885085747
https://www.osterwalderlab.com 20-11-2014 01:24:32
180 Tweet
200 Followers
168 Following



How to test the functional impact of noncoding variants in vivo? Happy to share our work led by Ethan Hollingsworth where we developed dual-enSERT, a new method that enables rapid, quantitative comparison of human enhancer variant activities in live mice. Check this Tweetorial for details



Bonkers paper! From TF cooperatively and interdependence to crystal structure to biochemistry to human genetics! Tour de force from Joanna Wysocka's team including Seungsoo Kim, Jussi taipale, Sahin Naqvi, and others: cell.com/cell/fulltext/…


Our preprint characterizing mouse developmental Enhancer—Promoter interactions by Zhuoxin is out today Nature Genetics rdcu.be/dBRPu See also a complementary study on fly Enhancer—Promoter interactions from Eileen Furlong nature.com/articles/s4158…


I am extremely happy to share with you today my latest work now in #bioRxiv at Guillaume Andrey lab. Don't miss it if you want to know how temporal constraints on enhancer usage shape the regulation of limb gene transcription! biorxiv.org/content/10.110…

Nice correlation between massively parallel reporter assays (MPRAs) and mouse enhancer assays and great neurodev enhancer catalog. Great work and collaboration from Michael Kosicki, @DianneLaboy, Len Pennacchio and many others. biorxiv.org/content/10.110…

How do enhancers work over distances that sometimes exceed megabases? Excited to share our work led by Grace Bower where we uncover a unique sequence signature globally associated with long-range enhancer-promoter interactions in developing limb buds: biorxiv.org/content/10.110… 1/






Updated VISTA Enhancer Browser, 7 years in the making, out in Nucleic Acids Res! >4,500 transgenic in vivo enhancer experiments for all your developmental biology, human variation and #evodevo needs. enhancer.lbl.gov #enhancers #embryos doi.org/10.1093/nar/gk…


🧬 Forschende des BioMedical Research, Faculty of Medicine, University of Bern und der Insel Gruppe haben gemeinsam mit U Calgary und Berkeley Lab in einer "Genwüste" 🏜️ wichtige Steuerungselemente für die Embryonal- und Herzentwicklung identifiziert: sohub.io/z647.
