1/ Endovascular stroke treatment (EVT) is one of the biggest success stories of medicine! In clinical reality, the question is no longer “Who to treat?” but: “Who should we NOT treat???” A case-based tweetorial about futile recanalization … #NeuroTwitter #SharedDecisionMaking

Our meta-analysis on the value of intravenous thrombolysis in stroke patients with large vessel occlusion has been published in The Lancet. Great international team effort! ⁦Johannes Kaesmacher⁩ ⁦Thomas Meinel⁩ ⁦Manon Kappelhof⁩ sciencedirect.com/science/articl…

Winter School '23 was absolutely wonderful - 4 days of outstanding quality discussions on stroke treatment and research, getting to know passionate and talented colleagues, all to a backdrop of magical Bern in winter. Register now for the '24 edition - see you there! 🏔️

#ASPECTS #stroke training & certification📜 now available via Let's Get Proof University (free, no sign-up required): ▶️letsgetproof.com/pages/aspect-i… ...check out those annotated DICOM example cases🧐 ▶️Want to get involved? Join the ASPECTS working group: letsgetproof.com/working-groups…

Urs Martin Fischer Johannes Kaesmacher and team SWIFT DIRECT Trial from Stroke Research Center Bern as well as all the incredible #AllEyesOnIris collaborators! Fabiano Kilian Treurniet Manon Kappelhof 👏👏👏💪💪💪

2/ No matter your vote, check out Manon Kappelhof & Johannes Kaesmacher's editorial on the available evidence, including the recent study by Dhillon et al. in SVIN. We await the ongoing RCT LATE-MT (NCT05326932), but until then... 👇🏽 doi.org/10.1161/SVIN.1…

We. Are. OFF 🚀 11th edition of the Stroke_Winter_School has officialy started ⭐️ During this week Bern will be the center of #stroke education with A-level faculty for young neurologists, neuroradiologists, neurosurgeons and all other neuro-enthusiasts!

It's a wrap. The 2024 StrokeWinterSchool ends after 4 days of hands-on stroke training, case discussions and interactive seminars. Many thanks to all participants, faculty, European Stroke Org ESMINT Society ESNR and industry sponsors who made this year's edition another success!

Time matteres for IVT prior to thrombectomy! Great presentation of Johannes Kaesmacher from Stroke Research Center Bern at ISC and simultaneous publication in JAMA #alleyesoniris Fabiano Manon Kappelhof Kilian Treurniet Urs Martin Fischer jamanetwork.com/journals/jama/…

Time matteres for intravenous thrombolysis prior thrombectomy - results of our meta-analysis just published in JAMA. Many thanks to Johannes Kaesmacher and the whole IRIS Team for the great collaboration.Johannes Kaesmacher Fabiano Manon Kappelhof Kilian Treurniet

Magic MT RCT 🇨🇳 shows therapy effect of MMA Onyx embolisation in cSDH! Congratulations! European Stroke Org ESMINT Society Medtronic Neurovascular

Running rtPA upon recanalization with MT: data from the IRIS collab show no effect of running IVT on outcomes (p for interaction = 0.23) and no interaction for the TICI score. Congrats to Johannes Kaesmacher & IRIS team 👏 #AllEyesOnIRIS Fabiano #ESOC2024 #VoiceOfStroke

Acute stenting with or without IVT in patients with tandem lesions❓️Data from the IRIS collaboration show no effect modification of IVT on 90D mRS. Lytics should be given when possible! Congrats Fabiano on the presentation 👏 #AllEyesOnIRIS #ESOC2024 #VoiceOfStroke

Check out this #Stroke #EditorPick, "Endovascular Thrombectomy Alone for Large Vessel Occlusion: A Cost-Effectiveness Evaluation Based on Meta-Analyses." #AHAJournals Manon Kappelhof Natalie LeCouffe Fabiano ahajournals.org/doi/full/10.11…

What are the 10 most common pitfalls in non-inferiority trials? Check our latest article in Stroke! Johannes Kaesmacher Stroke Research Center Bern Kilian Treurniet Manon Kappelhof ahajournals.org/doi/10.1161/ST…

Article Commentary: "Endovascular Thrombectomy Alone for LVO: A Cost-Effectiveness Evaluation Based on Meta-Analyses" In this #BloggingStroke post, Rami Z. Morsi, MD discusses #Stroke article by Nguyen et al. Manon Kappelhof Natalie LeCouffe Fabiano ahajrnls.org/40ezlUp

🧵New chapter in the #STROKE #RCTSeries 📕: This topical review by Fabiano et al. provides stroke clinicians and researchers with a general overview of non-inferiority trials and a deeper understanding of their pitfalls. #AHAJournals ahajournals.org/doi/full/10.11…

🚨 New paper alert! 🚨 Should carotid tandem lesions influence the decision to give IVT for patients that can directly undergo EVT? New IRIS study in Lancet Neurology: authors.elsevier.com/a/1knz55FFzL42… #Stroke #EVT #IVT Kilian Treurniet Johannes Kaesmacher Manon Kappelhof Urs Martin Fischer

🚨Can 24h NIHSS be a primary outcome for acute stroke RCTs? 24h NIHSS results aligned with 90d mRS in 84% of RCTs, but early NIHSS risks misclassifying 1/4 patients doi.org/10.1161/JAHA.1… Johanna Ospel, MD PhD Manon Kappelhof Rosalie McDonough Michael D Hill Mayank Goyal Stroke AHA/ASA DCNS Calgary

Does intravenous thrombolysis prior endovascular treatment (EVT) increases the risk of intracranial haemorhage compared to EVT alone? Check our latest article in JAMA Neurology! Stroke Research Center Bern Johannes Kaesmacher Fabiano Cavalcante Kilian Treurniet Manon Kappelhof Thomas Meinel