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Very cool artistic rendering of the structure from our recent manuscript!

The bile acid-sensitive ion channel is gated by Ca2+-dependent conformational changes in the transmembrane domain | bioRxiv biorxiv.org/content/10.110…

Using mineral deposits from Herbstlabyrinth Cave, researchers developed a precise chronology of volcanic sulfur spikes and were able to link the Laacher See Eruption to a previously unidentified sulfate spike in the Greenland ice core record. Learn more: scim.ag/4gW0BxU

Very excited to share our latest work published today: science.org/doi/10.1126/sc… Congratulations to Tommy Shi, Ismayn Ditter and Adam Oken. Thank you to PNCC Claudia Lopez 🇦🇷 for the outstanding microscopy/Cryo-EM support. NIH Common Fund ASCI

Dynamic molecular portraits of ion-conducting pores characterize functional states of TRPV channels. doi.org/10.1038/s42004…

Navigating the worlds of research and patient care requires both precision and passion, and OHSU News' Dr. Steven E. Mansoor finds fulfillment in this work as a physician-scientist. ohsufoundation.org/stories/the-ch…

So thankful for all the support I’ve received from OHSU, the Knight Cardiovascular Institute, the Department of Chemical Physiology and Biochemistry, the Vollum Institute, the Pacific Northwest Cryo-EM Center, the NIH, the AHA, and generous members of the Oregon community.

Excited to share our latest work! 🚀 A great achievement made possible by an incredible multidisciplinary collaboration. Even more remarkable, the high-resolution cryo-EM structures of human P2X7 from Steven E. Mansoor's group provided the foundation for this exciting discovery.

Human P2X4 receptor gating is modulated by a stable cytoplasmic cap and a unique allosteric pocket. @ScienceAdvence. Check this #membrane #protein in the UniTmp database: pdbtm.unitmp.org/entry/9bqh science.org/doi/10.1126/sc…

A manuscript from our group published a couple of months ago.

Please join us for our free monthly CryoEM Current Practices Webinar Series. Adam Oken will discuss "Small-Molecule Modulation of the P2X7 Receptor Revealed by Cryo-EM." Register at cryoemcenters.org/events/

Adam Oken from our lab gave a great presentation summarizing some of the work we have been doing. If you are interested, please watch a recording of his seminar, linked here: youtu.be/IdcoLJc7X8M

Late week one of our long time users Adam Oken, from the MansoorLab gave a great talk on their research. Check out his an other's Cryo-EM Current Practices Webinar talks on our webinar archive. cryoemcenters.org/webinararchive/

Navigating the worlds of research and patient care requires both precision and passion, and OHSU News' Dr. Steven E. Mansoor finds fulfillment in this work as a physician-scientist. ohsufoundation.org/stories/the-ch…

A true Physician-Scientist and OHSU School of Medicine #MDPhD alum, Dr. Steve Mansoor, sharing details about how his lab uses #DrugDesign principles to fit the ligand into the target receptor like a jigsaw piece. 🧩Thank you for your presentation Dr. Mansoor! OHSU News OHSU Knight Cardio OHSU School of Medicine

The KCVI research retreat was a great success this year. Very happy to participate. Looking forward to making this an annual event!

Meet the Changemakers! OHSU News' Dr. Steven E. Mansoor finds fulfillment in this work as a physician-scientist. ohsufoundation.org/stories/the-ch…

OHSU scientists using #CryoElectron microscopy have discovered the structure and shape of key receptors connecting #neurons in the brain’s cerebellum, which plays a critical role in coordinating movement, balance and cognition. news.ohsu.edu/2025/06/23/ohs… #OHSUResearch