Markus Sommer (@markusjsommer) 's Twitter Profile
Markus Sommer

@markusjsommer

Principal Investigator, Bioinformatics, NBACC

markus.bio

PhDone @JohnsHopkins @JHUBME in the Salzberg Lab

ID: 2922445794

linkhttps://scholar.google.com/citations?user=2MR9XAgAAAAJ&hl=en calendar_today08-12-2014 08:19:48

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241 Followers

213 Following

𝕐 (@nomad421) 's Twitter Profile Photo

Markus gave an excellent talk (the last of the meeting) at #biodata22 on this work. It's very exciting, and I'm glad to see it published now. I look forward to reading the paper!

Steven Salzberg πŸ’™πŸ’› (@stevensalzberg1) 's Twitter Profile Photo

The final version of our paper on using protein structure to determine functionality is out in eLife - the journal: doi.org/10.7554/eLife.…. Some of the prettiest figures we've had in any recent paper, like the one here. Led by Markus Sommer, plus Mihaela Pertea @thesteinegger et al.

The final version of our paper on using protein structure to determine functionality is out in <a href="/eLife/">eLife - the journal</a>: doi.org/10.7554/eLife.…. Some of the prettiest figures we've had in any recent paper, like the one here. Led by <a href="/markusjsommer/">Markus Sommer</a>, plus <a href="/elapertea/">Mihaela Pertea</a> @thesteinegger et al.
Steven Salzberg πŸ’™πŸ’› (@stevensalzberg1) 's Twitter Profile Photo

first paper of 2023 for us: a gap-free, fully annotated genome of a southern Han Chinese individual, led by Kuan-Hao Chao, with Aleksey Zimin and Mihaela Pertea. We used the #T2T CHM13 genome to fill gaps academic.oup.com/g3journal/adva…

Steven Salzberg πŸ’™πŸ’› (@stevensalzberg1) 's Twitter Profile Photo

ORFanage is new system by Ales Varabyou Beril Erdogdu and Mihaela Pertea that finds protein-coding regions in gene annotation, esp. in RNA-seq assemblies. See what it can do in our new preprint biorxiv.org/content/10.110…

Ales Varabyou (@av_sparrow) 's Twitter Profile Photo

Accurate DTU detection in complex diseases with SPIT by Beril Erdogdu,Stephanie Hicks, PhD,Steven Salzberg πŸ’™πŸ’›,Mihaela Pertea! Findings include previously unreported DTU events in 6 genes associated with schizophrenia. Also available on Google Colab -> Learn more at biorxiv.org/content/10.110…

Steven Salzberg πŸ’™πŸ’› (@stevensalzberg1) 's Twitter Profile Photo

watch out SpliceAI, there's a new kid on the block, Splam! More accurate at predicting splice sites and much faster too. Check out the code and the pre-print in the thread from Kuan-Hao Chao below.

Steven Salzberg πŸ’™πŸ’› (@stevensalzberg1) 's Twitter Profile Photo

Our paper on the human gene annotation catalog CHESS, which now includes all of MANE and a more rigorous definition of genes of all types. With Mihaela Pertea Ales Varabyou @thesteinegger Markus Sommer Beril Erdogdu @IliaMinkin and others: genomebiology.biomedcentral.com/articles/10.11…

Josh Welch (@labwelch) 's Twitter Profile Photo

How does alternative splicing regulate protein structure to enable cell-type-specific protein functions? With Matthew O’Meara, we used AlphaFold2 + scRNA-seq to investigate this question in our latest preprint. biorxiv.org/content/10.110β€¦πŸ§΅

Steven Salzberg πŸ’™πŸ’› (@stevensalzberg1) 's Twitter Profile Photo

Three bioRxiv releases from my lab last week, and one more today! From postdoc Markus Sommer, his new eukaryotic gene recognizer, PSAURON (the "p" is silent), a successor to his bacterial gene finder Balrog #LOTR biorxiv.org/content/10.110…

Steven Salzberg πŸ’™πŸ’› (@stevensalzberg1) 's Twitter Profile Photo

Check out our just-published AI-based (temporal convolutional network) system, PSAURON, for predicting eukaryotic proteins, from Markus Sommer. We used a similar method in BALROG, our bacterial gene finder. Note: the "P" is silent in PSAURON 🀣 academic.oup.com/nargab/article…