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Late breaking at #ESCCongress: In a trial involving older patients with myocardial infarction and multivessel disease, physiology-guided complete revascularization led to a lower risk of cardiac events than culprit-only PCI. Full results of the FIRE trial:

Amsterdam auditorium is on #FIRE 🔥 #FIRETrial #ESC2023 European Society of Cardiology #Ferrara ▶️ Now on NEJM

Check out our latest investigation on the prognostic value of Syntax Score II 2020 corrected for flow-limiting lesions and its ability to better address treatment by benefit prediction among patients with left main or multivessel disease! mdpi.com/2077-0383/12/1…

In young and middle-aged patients with myocardial infarction and multivessel coronary artery disease, the benefits of pursuing complete revascularization — by treating nonculprit lesions as well as culprit lesions — are well established. Full FIRE trial Research Summary:

#ESC LBCT presenter + 1st author NEJM + finalist #TCT ... I can tell Simone Biscaglia is friend of mine... 😁😁😁

⚡️Just published ❤️‍🔥PCI is the most commonly performed revascularisation procedure in the treatment of coronary artery disease ❤️‍🔥Coronary physiology plays a role to optimise treatment strategy, improve clinical outcomes & QoL ❤️‍🔥Read ⬇️ work by Francesca Rubino heart.bmj.com/content/early/…

Ticagrelor Monotherapy reduced bleeding without increasing ischemic events in 7,529 ACS patients from TWILIGHT and TICO trials pooled analysis Our study led by Dr Roxana Mehran and presented by Usman Baber at #TCT2023 simultaneously published in Circulation ahajournals.org/doi/10.1161/CI…

Physiology-guided #PCI was superior to conventional angiography in achieving optimal post-PCI #FFR values in patients undergoing #CHIP, according to AQVA II trial findings. bit.ly/3S7yVg9 #TCT2023 #JACCINT #CardioTwitter

Changes in coronary venous pressure led to a decrease in coronary microvascular resistances in a randomized, sham-controlled study in patients with microvascular angina. The implications for chronic therapy deserve investigation. ja.ma/45rllag

In patients w/ cardiovascular disease & overweight or obesity but no diabetes, semaglutide was superior to placebo in lowering the risk of major adverse cardiovascular events at a mean follow-up of 39.8 mos. Full SELECT trial results: nej.md/465pj91 #AHA23 AHA Science

The next iteration of #TAVR practice? TAVR in non-surgical centres. #PCRLV

But... Mortality is high due to nature and severity of complications.

Zerofluoro AFib ablation! The APRONLESS study just published on JAFIB&EP! MatteoBertini Francesco Vitali cristina balla Martina De Raffele Federico Marchini Marta Cocco jafib-ep.com/journal/novemb…

doi.org/10.1111/eci.14… Baim Institute European Journal of Clinical Investigation

great work from my good friends Simone Biscaglia & Gianluca Campo about superiority of physiology over angiography in #CHIP patients. I hope colleagues will start updating PCI to 2.0 in #CHIP cases (FFR or imaging) jacc.org/doi/10.1016/j.…

This study explored the impact of aortic valve replacement on coronary flow reserve (CFR) in patients with severe aortic stenosis and its association with changes in left ventricular mass and function. After valve replacement, CFR in the left anterior descending artery improved

#EuroPCR #JACCINT LBCT SimPub: QFR can predict non-culprit lesions at higher risk of future events & is non-inferior in guiding treatment compared to the current gold-standard, wire-based physiology. bit.ly/3yfi2Ip #cvMI Gianluca Campo Ignacio J. Amat Roberto Scarsini

🔥🔥🔥 Check out the simultaneous publication on the NSTEMI vs STEMI subanalysis of FIRE Trial JACC Journals 🗣️Consistent benefit of physiology-guided complete revasc in NSTEMI and STEMI patients!

🎉🍾🎯 Another dream came true! Being in the same Hotline European Society of Cardiology session with my mentor, friend & older brother Gianluca Campo We did it! 🔥FIRE 🌍 EARTH elementrials.org Thanks to Barbara Casadei for the picture!

Marta Cocco Simone Biscaglia