Cells located in the midline of the embryo play crucial roles in development. These cells often influence cell fate decisions and guide axons to establish bilateral connections. Despite their importance, studying these transient cells and their complex interactions has been

Thrilled to share that I will join Johns Hopkins University Johns Hopkins BME as an Assistant Professor in 2025! The Yang Lab will develop novel bioelectronics and biomaterials for brain-machine interfaces, regenerative medicine, and the study of human neural development and diseases.

Hard to believe, but our lab at Stanford University celebrates its 10th anniversary this year. It feels like we started just yesterday, yet so much has happened. Here's a quick selfie with this remarkable group of scientists, working with more enthusiasm than ever to unravel the

Assembloids have emerged as a powerful tool for studying previously inaccessible processes of development and tissue homeostasis. While initial #assembloids were developed to model human brain development, there are now models for most organ systems, from the bladder to the

I’m excited to share that my review article on #assembloids just dropped in Cell Stem Cell! Check out the post below to learn more about this fast-evolving field and its potential for uncovering new insights into human biology and finding cures for diseases.

We recently introduced human neural loop #assembloids created from 4 parts to study the cortico-striato-midbrain-thalamo-cortical pathway Here’s a short animated summary of the work led by Yuki Miura and Ji-Il Kim in the lab

Great to see our paper online! Amazing collaboration with Neal Amin over the years. With invaluable input from Konstantin Kaganovsky, Massimo Onesto, Jin, Yuki, James Patrick McQueen, MS, CSCS, Noah, and others in Sergiu P. Pasca group.

Our latest work is out today in Science Magazine: a self-organizing system that models organizer-driven patterning and commissural axon guidance in human neural development. This was achieved with human midline #assembloids by combining floor plate and spinal cord #organoids