Reading papers today and was struck by this gem from Sydney Brenner (Sequences and Consequences, Phil. Trans. R. Soc. B 2010). 10 years on, I don't think we're close to having it down yet. We've at least sent RNA, proteins, metabolites and others up to keep it company though.

Microscope modifications underway!

NIH-Funded Systems Biology Short Course at UCI, Jan 13-31, 2020 sites.uci.edu/ccbsshortcours…

#Steampunk #dynein made by 3D printer #Form3

Foreground is finished on the immunological synapse painting--so many wiggly lines to paint! These paintings were so much easier before we began to understand the importance of unstructured proteins...

New video! Which of these online ratings is better? youtu.be/8idr1WZ1A7Q

Have you wondered which great biophysics seminars are happening somewhere around the world, which you could have joined in the Zoom era if you only knew about them? Introducing world-wide.org/Physics-of-Lif… World Wide Physics Of Life - a clearinghouse of virtual seminars in bio/physics. /1

In this video, CGP Grey talks about what it's like to write a paper. youtu.be/ua4QMFQATco

This was my draft for the conclusion: Kinesin potentially has the ability to bind 10-100 times faster than previous estimates. This is exciting because it gives a very different picture for how cargos may bind to microtubules in the cell. It is also deeply confusing.

The number of "how the...?" moments in this video is extraordinary

How to understand cells, tissues and organisms as agents with agendas – aeon.co/essays/how-to-… via Aeon Magazine My colleague Michael Levin has opened up a whole world of phenomena that are illuminated by adopting the intentional stance. He's been teaching me a lot. Check it out.

It'll be interesting to see how much people trust these structures. How much would you invest in testing a hypothesis based on one? Make a cell line? A mouse model? Design a drug? nature.com/articles/d4158…

Recommended reading! Very well written article which informs basically every question and thought I had about AlphaFold2.

A new high watermark for communication of scientific results. Wonderful!

The 2021 edition of the Physical Biology of the Cell class that Rob Phillips teaches at Caltech is available on YouTube. If you want to learn about the interface between physics and biology please check the class. Help me retweet this to reach students! rpgroup.caltech.edu/aph161/syllabus

The PhD program of the MPI-CBG Dresden, the IMPRS-CellDevoSys, is accepting applications until October 30, 2023 for fully funded PhD positions. Apply now if you are enthusiastic in conducting research with us and want to be part of our community. …online-application.cmcb.tu-dresden.de/ausschreibung?…

New #preprint! A great #devbio #biophysics collaboration MPI-CBG Dresden Center for Systems Biology Dresden with Zerial Lab, led by Julien Delpierre: Hepatoblast iterative apicobasal polarization is regulated by extracellular matrix remodeling, available at biorxiv.org/content/10.110…. @mpipks

New #review on "Shaping Epithelial Lumina under Pressure" now published #BiochemSocTrans Portland Press! Matt Bovyn and I review lumen formation mechanics and discuss the emerging role of nonlinear mechanics in the elongation of tubular lumina. doi.org/10.1042/BST202…