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MWAS and brain health PheWAS of >4000 proteins in the Generation Scotland cohort. Danni Gadd's latest paper is now out in Nature Communications. Paper here: rdcu.be/cTmri YouTube summary: youtu.be/ngq3z6xk0fY

How to choose a subset of CpGs for EWAS or DNAm prediction... @RobertHillary looks at statistical and biological properties of Illumina array content and tries to decide! Paper now out in Clinical Epigenetics. rdcu.be/cTtUL

We are recruiting a postdoc in the Program for Complex Trait Genomics in the University of Queensland to work on developing methods to understand trait genetic architecture across human populations. Join us at the beautiful east coast of Australia! uq.wd3.myworkdayjobs.com/uqcareers/job/…

Taking UQs new HPC Bunya for a spin! Advantage of being an early adopter - doubt I will ever get that number again. UQ Research Computing Centre

UQ Science Congratulations to Dr Yengo for being awarded the Ruth Stephens Gani Medal for his contributions to human #genetics. The medal honours the contribution to science in human cytogenetics by the late Ruth Stephens Gani. #ShineDome22 UQ News

I'm very happy to see my 2nd paper from my PhD finally published in Human Molecular Genetics! We showed that rare SNPs underlie outlying levels of DNA methylation, which is stable across time doi.org/10.1093/hmg/dd…

An overview of DNA methylation-derived trait score methods and applications: new paper out Genome Biology Thanks Naomi Wray Danni Gadd Jonathan Mill Eilis Hannon McRae Lab I really like this one genomebiology.biomedcentral.com/articles/10.11…

Blood-based genome-wide DNA methylation correlations across body fat and adiposity-related biochemical traits biorxiv.org/cgi/content/sh… #bioRxiv

New preprint from the lab. We adapt genetic correlation methodology to DNA methylation (or any 'omics data) and examine correlations between adiposity related traits. New insights to sex-specific DNA methylation associations and the epigenetic relationship between traits.

Lightning talk by Monalisa Hota on deconvolution of cell composition in endometriosis. Come have a chat in the poster session. #GeneMappers2023

Tian Lin from PCTG presenting a library of iPSC derived motor neurones for the study of MND #GeneMappers2023

First of a double header by the lab! Beilei Bian presenting on antagonistic variants in the human genome. #GeneMappers2023

Second part of McRae Lab double header! Alesha Hatton presenting DNA methylation correlations. Check out our preprint biorxiv.org/content/10.110…. #GeneMappers2023

Great talk by Isabelle McGrath on cross-trait analyses with endometriosis and comorbities #GeneMappers2023

Xiaotong Wang from PCTG on the reason why we can get the weird observation of prediction R^2 being higher than SNP h^2! #GeneMappers2023

Wrapping up a great day at #GeneMappers2023. Today 9 of the 21 talks were from Institute for Molecular Bioscience PhD students or EMCRs!

Arrived to the inaugural "Dress like Allan" day at the office today!

Hi Everyone, Offering two PhDs in sunny Oz- 1 on developing statistical methods to investigate causality: Sometimes Correlation does Equal Causation: Developing Statistical Methods to Determine Causality Using Genetic Data at University of Queensland on FindAPhD.com

The McRae Lab at Institute for Molecular Bioscience are using FightMND's IMPACT grant, jointly awarded with MND & Me Foundation, to identify MND biomarkers to speed up diagnosis. Learn more about Allan's project at: fightmnd.org.au/wp-content/upl… #IMBATUQ #FightMND #MND #MNDandMe

Exchange between Institute of Genetics and Cancer and Institute for Molecular Bioscience allowed collaborative genomics research by PhD students Danni Gadd (MarioniGroup) and Alesha Hatton (McRae Research Group), including utilising the Generation Scotland dataset. ed.ac.uk/centre-genomic…