🔥The 9th Round of Easy Loan, Earn $40 Reward is in progress❗️ ⏰ Promotion Period: January 15th - Feburary 15th, 2025 👉 Register now and check more details at gate.io/campaigns/358

My choice this week in Science Magazine nature.com/articles/s4155… Frydman Lab Ranen Aviner

I'm delighted to announce our team's latest publication in Nature Cell Biology ! you can now learn more about the fundamental role of CD63 in cholesterol sorting here: nature.com/articles/s4155… Thanks to all collaborators, institutions and financial supports !

👋Our June issue's live! Cover: #RNA binding in #glioblastoma 👉🏽Perspective: intrinsically disordered proteins & #aging clocks 🔬: #autophagy, #hTERT #Rloops, #PhaseSeparation #Leukemia, #proteostasis #HuntingtonsDisease, #oocytes & more! nature.com/ncb/volumes/26…

Nature research paper: dsRNA formation leads to preferential nuclear export and gene expression go.nature.com/3Xq4aWl

Why do eggs in ovaries last for decades? Long-lived proteins may be key! Read more about our recent Nature Cell Biology study and a related eLife - the journal study by NU Duncan Lab in this nice news article in Science Magazine. science.org/content/articl…

See: doi.org/10.1038/s41556… A close-up view of mRNA organization and regulation during active translation in germ granules! Congrats to Roy Chen, William Stainier, and our collaborators Jeremy Dufourt and Mounia Lagha! Nature Cell Biology!

💫NEW: Schuh Lab, Juliane Liepe, Urlaub & co analyse #proteostasis in mammalian #oocytes and ovaries: the maintenance of oocytes involves exceptional protein longevity, and many of the extremely long-lived proteins decline as the #ovary ages. nature.com/articles/s4155…

👋🏻Our July issue's live! Cover: Unconventional secretion 👉🏼Reviews: #Rloops #GQuadruplex, #RNAlocalization 🔬on: #lysosomes #endosomes #cholesterol #oocytes #longevity #migrasomes #melanoma #ProstateCancer #embryogenesis #chromatin & more! nature.com/ncb/volumes/26…

Spermidine is essential for #fasting-mediated #autophagy and #longevity Nature Cell Biology nature.com/articles/s4155…

👋🏾Our August issue's live! Cover: Multi-#organelle units 🔬on: #medulloblastoma #AlternativeSplicing, #HydrostaticPressure in #macrophages, #synuclein #BiomolecularCondensation, #TranscriptionFactors, #immunosurveillance of #SenescentCells & more! nature.com/ncb/volumes/26…

📑: Julia Magdalena Majewska Amit Agrawal et al fr/Valery Krizhanovsky show that p16-expressing senescent cells enhance the stability of the immune checkpoint PD-L1, by downregulating its proteasomal degradation to accumulate in ageing and chronic inflammation. nature.com/articles/s4155…

Excited to share our new paper Nature Communications. bit.ly/3WUkxbJ Single-nucleosome imaging reveals that condensins act as molecular crosslinkers, locally constraining nucleosomes to organize mitotic chromosomes. Nucleosome-nucleosome interactions constrain whole chromosomes.

When it comes to dealing with stress, cells are resourceful. A paper @nature describes one strategy whereby, in response to oxidative stress, an autophagy-like process clears vesicles derived from the inner mitochondrial membrane. search.app/ftJtzSrYvqNTAA…

Thrilled to share our latest story Nature Cell Biology on a new way to control protein localization without exogenous triggers (e.g., light/rapamycin)—take advantage of endogenous triggers in dividing cells! Free link: rdcu.be/dSlrS Regular link: nature.com/articles/s4155… 1/4

Thrilled to share our new paper in Science Magazine, in which we identify p62/SQSTM1 as a critical regulator of micronuclei 🧬🔬🧫 #ScienceResearch science.org/doi/10.1126/sc…

Can we use CRISPR screens to identify genes that drive neural stem cell aging? Super excited to see this work published nature! Huge congrats to Tyson @ruetz_tyson, Angie Pogson, Chloe Kashiwagi, and all authors! Great collaboration with Michael C Bassik! nature.com/articles/s4158…

💫NEW: @fran_bottanelli, Alexander Stockhammer, Petia Adarska & co describe ARF1 compartments as the site of adaptor- and clathrin-dependent post-#Golgi sorting. Department Biology, Chemistry, Pharmacy FU Berlin Freie Universität nature.com/articles/s4155…

👋Our October issue's out! Cover: Heritable #Amyloids 👉🏻Comment on #EmbryoModels 👉🏼Review: #mitophagy #pink1 #neuroprotection 🔬on: #gastruloids #mechanobiology #Golgi #polycomb #epigenetics #HSF1 #antitumor #Pbodies #cancer & more! nature.com/ncb/volumes/26…

🚨 Super psyched this story is finally out!   Herculean effort and 3rd chef d’oeuvre in @NatCellBio by @patriziaromani in just 5y, where we describe #mitochondrial #mechanotransduction.   nature.com/articles/s4155…   Megathread with bonuses ⬇︎⬇︎⬇︎

👋🏻Our November issue's out! Cover: Imaging #Ovulation 👉🏼Comments on #embryo models & #MembraneContactSites 🔬on: #PlasmaMembrane #endosomes #CellDeath #metabolism #mTOR #BiomolecularCondensation #gastruloids #organoids #ProteinQualityControl & more! nature.com/ncb/volumes/26…