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Congrats grad students Michael Burke, Duc Chu, Benjamin Groff, Alexander Hegg, Haotian Huang, Jana Jelusic, Jaehoo Lee, Jessica Mohsen, Kristian Olesen, Thomas Regan, Soren Rozema, Anastasia Saar, Bo Shang, Santino Stropoli, Zhi Xu, and Jiayun Zhong on the fellowship awards!

Exploiting natural riboswitches for aptamer engineering and validation academic.oup.com/nar/advance-ar…

In Nucleic Acids Res, with postdoc Michael Mohsen, undergrad Matt Midy, and grad student Aparaajita Balaji, Ph.D., we exploit the guanine-I #riboswitch architecture to engineer genetic switches for #quinine and #caffeine. Next challenge: switches for gene therapy applications. doi.org/10.1093/nar/gk…

Zhipeng Lu and I wrote a perspective on RNA cross-linking. Check it out! pubs.acs.org/doi/10.1021/ja…

Check out our paper on "Screening for small molecule inhibitors of SAH nucleosidase using an SAH riboswitch" here: authors.elsevier.com/c/1gYzn_4mX4Lh…

A clever "Graftamer" approach from Ronald Breaker's lab to in vitro select aptamers that can function in vivo. Exploiting natural riboswitches for aptamer engineering and validation academic.oup.com/nar/article/51…

Mathijs constructed a fluorogenic probe for the polymerase TdT, out now! onlinelibrary.wiley.com/doi/10.1002/an…

A Quenched Size-Expanded Nucleotide Reports Activity of the Leukemia Biomarker Terminal Deoxynucleotidyl Transferase (TdT) (Willem A. Velema et al.) VelemaLab #openaccess onlinelibrary.wiley.com/doi/10.1002/an…

What natural talent would Willem Velema like to be gifted with? VelemaLab Find out on his #IntroducingAngewandte page onlinelibrary.wiley.com/doi/10.1002/an… x.com/angew_chem/sta…

Commencement speaker⁦⁩ Sana Marin, former prime minister of Finland, thanks ⁦New York University⁩ for shaping the world and for being the “coolest university in the coolest city”

A new and unexpected project for us: today our paper on DNA damage in cooked foods was published- pubs.acs.org/doi/10.1021/ac…

Coming soon to a journal near you! Here's an early peak at the research I've been involved in during my post-doc!

Check out this article in Stanford News! They highlighted our recent work. news.stanford.edu/2023/06/12/stu…

Noncoding translation: Quality control in the BAG: cell.com/molecular-cell…

RNA instability is an important problem for RNA therapies - check out our new paper on a simple solution: temporarily block 2'-OH groups rdcu.be/dfpLb

New in #synbio: 🦠 In vitro selection techniques for developing #riboswitch-inspired #aptamers for new ligands demonstrate improved in vivo functionality: ibit.ly/TL2Q Michael Mohsen and Ronald Breaker

1/Today I am thrilled to announce, after years of work, our team Fervo Energy has developed a major advancement in geothermal, proven it at the field scale, and is set to deliver commercial next-gen geothermal decades ahead of schedule. THREAD. bloomberg.com/news/articles/…

Our paper describing the interaction of multiple protein-targeted drugs with cellular RNAs has appeared in Nature Chemistry - the study used acylation to trap drugs on RNAs doi: 10.1038/s41557-023-01309-8

Engineered Branaplam Aptamers Exploit Structural Elements from Natural Riboswitches. dlvr.it/T97Mnc

[ASAP] Engineered Branaplam Aptamers Exploit Structural Elements from Natural Riboswitches #science #publication #research #journal lifescience.net/entries/688524…