Single-cell folks, what cell sorters are you using to FACS in (384-well) plates? We are continuously disappointed with BD Biosciences customer support. Please RT!

Just published an article exploring how transcriptional bursts affect random autosomal monoallelic expression. Updated from the preprint with new Smart-seq3 data! PLOS Comp Biol Michael Hagemann-Jensen Christoph Ziegenhain Rickard Sandberg dx.plos.org/10.1371/journa…

Less is more! Next iteration of Smart-seq3, called Smartseq3xpress. Now with less volume, hassle, PCR cycles, time and cost, for more complexity, convenience and throughput. doi.org/10.1101/2021.0…

Thrilled to get the opportunity to talk about Smart-seq3xpress in a webinar hosted by CYTENA / DISPENDIX next wednesday! Tune in if you want to hear me go on about nerdy scRNA-seq method details: dispendix.com/events/scalabl…

Join my team Karolinska Institutet! We’re recruiting a bioinformatics/computational postdoctoral fellow in Developmental biology ki.varbi.com/en/what:job/jo…

New study in Nature Genetics by KI researchers per_johnsson, Rickard Sandberg and others shows that high-precision tools that combine single-cell sequencing with mathematical calculations can identify the function of noncoding RNA. #Genomics #genes news.ki.se/new-tool-revea…

Delighted to finally see it out nature! The steps to generate human #HematopoieticStemCells (#HSC) rather than short-lived blood progenitors are poorly defined. Here we built a comprehensive #singlecell map tracing #HSC development in the human embryo. 🧵:rdcu.be/cLheL

So excited to see our ✨🧬'Molecular spikes'🧬✨ RNA spike-ins out in Nature Methods 📃 Since the preprint, we have completely overhauled the design & produced a completely new expanded set of spikes, so check it out: nature.com/articles/s4159… more below...⬇️

as usual fantastic to work with the usual suspects Gert-Jan Hendriks & Michael Hagemann-Jensen 😉

Today we are releasing the long-awaited Smart-seq3xpress protocol! It's been a long road of careful optimizations (Michael Hagemann-Jensen), and we are so proud of this cheap, fast scRNA-seq method with incredible data quality. full story in Nature Biotechnology: nature.com/articles/s4158…

Smart-seq3xpress enables single-cell RNA sequencing from full transcripts at high throughput go.nature.com/3ap1Hot

Thrilled to announce our paper is now online🎉 Big congratulations to Cheng Zhao for spearheading this work👏🏻 Special thanks to the entire team & the incredible collaborators on twitter Nicolas Rivron Reik Lab Jesica Romina Canizo @TheresaMSommer Michael Hagemann-Jensen pubmed.ncbi.nlm.nih.gov/35948369/

Very happy that our EEL method for large scale, high resolution spatial transcriptome profiling is out now! Thanks to all who contributed to this fun project! Especially Sten Linnarsson simone codeluppi Alejandro Mossi Camiel Mannens @jokubasj3

Excited to share our cell atlas of early human brain development! Miri Danan Gotthold Sten Linnarsson Thanks to all, especially: Lars Borm, Elin Vinsland, Lijuan Hu, Peter Lönnerberg, Kawai Ernest Arenas, Xiaoling He, Roger Barker, Xiaofei Li, Erik Sundström biorxiv.org/content/10.110…

Are you, like us, wondering WHERE’S that CLONE? On behalf of the ‘Spatial VDJ’ team, here's full-length BCR and TCR mapping in human tissue using spatial transcriptomics (Visium). biorxiv.org/content/10.110… Kim Thrane Qirong Lin @Jeff_Mold Jonas Frisén Joakim Lundeberg thread 1/n

Introducing synthetic thermostable RNase inhibitors to single-cell RNA-seq dlvr.it/T2RDSq

Are you interested in epithelial regionalization? cell.com/developmental-… Congratulations David Grommisch and Michael Hagemann-Jensen for the excellent work! Happy to see this out!