We have a fully funded Postdoc position for #Alzheimer functional genomics, integrating #IPSC models and multi-omic approaches to identify causal and druggable pathways. More info cruchagalab.wustl.edu/positions/ @WUSTL NeuroGenomics and Informatics Center

Beyond excited to share our new story on the discovery that FTD tau mutations disrupt lncRNA SNHG8 which promotes stress granule formation. We think this is relevant to FTD, AD & PSP ⁦The Rainwater Charitable Foundation⁩ ⁦CurePSP⁩ ⁦⁦The AFTD⁩ ⁦ nature.com/articles/s4138…

Check out the Celeste Karch‘s latest paper! We identified 15 lncRNAs significantly dysregulated in brain cells. Neurons with low SNHG8 levels had high levels of stress granules, which are rich in tau and can trigger tauopathies. nature.com/articles/s4138…

Trending in #Psychiatry: ooir.org/index.php?fiel… 1) Psilocybin use & improvements in mental health & wellbeing (Frontiers - Psychiatry) 2) Nature-themed video intervention may improve cardiovascular safety of psilocybin-assisted therapy for alcohol use disorder (Frontiers - Psychiatry) 3)

Planning to hire a scientist, science manager or leader? Don't miss this: sciencema.com/news/2023/10/1…. #ScienceResearch #LeadershipDevelopment

Try These Great Road Trips in Spain youtu.be/z3K0UxUY9yE?si… via YouTube Cuenca Consuegra Toledo Turismo Consuegra Turismo CLM #YouDeserveSpain

Don't forget to add this to your calendar!🗓️ Tomorrow November 7⃣ Frontotemporal Dementia and Related Disorders PIA will host a webinar on FTD genetics🧬, a great review & future of the field by RosaRademakersLab & Jennifer Yokoyama, moderated by Cyril & myself ⏱️5:00pm CET; 10:00am CST Registration link below

I chaired a search committee for an open Asst/Assoc Prof. We did 15 zoom pre-interviews. We had 7 questions that lasted 25 mins, w/ an opportunity for the candidates to ask questions at the end. Here are my tips from that experience, themed around song lyrics! Enjoy!

On my way to Lisbon #ADPD2024. Looking forward to seeing old friends, talking about science, and learning. It’s an honor to be supported by Celeste Karch The National Institute on Aging (NIA) @WUADRC. Don't miss my talk on 3/9 at 8:40 TAU Mechanisms: TFs regulators of early and late-stage Tauopathies

Interested in molecular signatures of #tauopathies dysregulated in earlier and more advanced phases of disease? Learn more about iPSC neurons, microRNA-induced neurons, and transcription factors at my talk at the #ADPD2024, March 9th at 8:40 TAU Mechanisms 03 Auditorium II

Thanks to Tauies Dr Mirfakhar & Dr Minaya for representing the lab so well with their amazing presentations at AD/PD - Advances in Science & Therapy Also check out Dr Bhagat’s on-demand talk #ADPD Miguel A. Minaya @WUADRC Reshma Bhagat

Happy WashU Psychiatry Research Day to those who celebrate! I’m lucky to be part of a lab who makes incredible discoveries and shows up to support one another 🫶🧬🔬🧪 WashU Psychiatry WashU Office of Neuroscience Research WashU Center of Reg Med @WUADRC

I’m super duper excited to share our latest preprint!!! Here, we used iPSC models to show that tau mutations cause broad defects in microglia. ⁦@WUADRC⁩ ⁦The Rainwater Charitable Foundation⁩ ⁦CurePSP⁩ ⁦WashU Center of Reg Med⁩ ⁦WashU Office of Neuroscience Research⁩ ⁩ ⁦CZI Science⁩ medrxiv.org/content/10.110…

Great day at Busch Stadium with the lab!! ⚾️🔬🧬🧪

Your Brain Age is less about mechanical ticks & more about entropic lifestyle & environment. In our Nature Medicine, brain clocks speed up due to dementia, exposome (economic inequality, pollution), gender-health disparities, & regional factors👉 nature.com/articles/s4159… 🧵1/6

A recent article in The @NYTimes highlights the inspiring story of Linde Jacobs, a nurse and advocate carrying a genetic FTD variant. Her journey exemplifies the resilience and determination needed to confront the challenges of living with a known FTD-causing gene while striving

Very proud of this new study from the lab! 🌟We identified a novel lncRNA, FAM151B-DT, that is disrupted across neurodegenerative diseases. medrxiv.org/content/10.110…

Super excited to share a new preprint highlighting a global collaborative effort to establish an African cell biobank for the study of neurodegeneration Mahmoud Bukar Maina PhD FRSA WashU Medicine Knight ADRC The Rainwater Charitable Foundation BioRTC medrxiv.org/content/10.110…

We’re pleased to announce the 3rd Iberoamerican ICSA online meeting, this time on Immunosenesce! 🗓️ May 29 | 🕓 16:00 CEST | 💻 Zoom 📩 Register: forms.gle/nZe8H2abUxWDT8… ℹ️ Info & past sessions: cellsenescence.info/iberoicsa #Senescence #Iberoamerica

🧵5 Top Free Alternatives to BioRender for Scientific Illustrations! These five websites offer free scientific illustrations for biologists. Great for presentations, research papers and other research communication needs. Save and share the post!