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Computation-aided designs enable developing auxotrophic #metabolic #sensors for wide-range glyoxylate and glycolate detection—spearheaded by Enrico Orsi w/a choral assembly of cool collaborators Nikel SEM Group Nature Communications #SynBio #OpenAccess nature.com/articles/s4146…

Check out this amazing work on engineering, characterizing and using six novel glyoxylate sensor strains led by Enrico Orsi and Helena Schulz-Mirbach🔥🎊🥳 Read Helenas nice post below to get the full picture.

📑📑📑#synthetic_biology @enricooorsi Helena Schulz-Mirbach Pablo Iván Nikel @pabnik.bsky.social SYBORG present a workflow for designing versatile auxotrophic metabolic sensors for glyoxylate and glycolate detection #BiotechNatureComms nature.com/articles/s4146…

🌿🔬How can we fix #CO2 more efficiently in biological systems? Our new study introduces the CORE cycle, a synthetic pathway that converts CO2 to formate at aerobic conditions and ambient CO2 levels! 🚀🦠 SYBORG Max Planck Institute for Terrestrial Microbiology nature.com/articles/s4146…

Seven Critical Challenges in Synthetic One-Carbon Assimilation and Their Potential Solutions—led by Giusi Favoino & Òscar Puiggené González Nikel SEM Group FEMS #Microbiology #Reviews #SynBio #Metabolic #Engineering academic.oup.com/femsre/advance…

Excited to share a main project from my PhD, out now in Nature Communications! 📝 We've designed and brought to life the “CORE cycle” – a new-to-nature pathway that provides a novel route for biological CO2 capture 🦠🌱 nature.com/articles/s4146… Take a look! Thread below... 🧵

I'm truly excited to announce our new publication in nature unraveling a central picture of the Methyl-coenzyme M reductase (MCR) activation machinery and it's strong ATP dependency - kudos to Anuj Kumar for the fantastic illustration! LINK: nature.com/articles/s4158…

📢We are thrilled that our Microbes for Climate (M4C) Cluster of Excellence has been selected for the 2025 Excellence Strategy! 🥳 Together with Philipps University Marburg, we're looking forward to some exciting #microbe research! Max Planck Society BangeBalcony #synbio #research

Implementing synthetic serine cycles in #Pseudomonas putida unlock methanol assimilation in our favorite bug with carbon conservation, led by Òscar Puiggené González · #SynBio #MetabolicEngineering #Methanol Trends in Biotechnology sciencedirect.com/science/articl…