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The direct link to our recent pre-print FBXW7 alleviates c-MYC repression of pyruvate carboxylase to support metabolic flexibility biorxiv.org/content/10.110…

I am very happy to share the first results from my postdoc in the Broz Lab. We investigated how the plasma membrane gets ruptured during #celldeath and discovered that cell swelling endows #NINJ1 filaments with the ability to induce rupture.

New paper 🚨 from Alexis A. Jourdain Fresh off the press on PNASNews!

📷 Looking for #volunteers for the 2025 #Swiss edition of the Pint of Science Festival, an international event focused on making science accessible and engaging for all. 🎉 Join #PINT25 Check our website and bellow!

An image from postdoc Emeline Recazens on the cover of PNAS! This picture highlights the recent Alexis A. Jourdain Department of Immunobiology at UNIL publication led by M. Foged on the role of mitochondrial RNA granules in innate immunity.

📢We're recruiting📢 Our lab at the University of Lausanne is looking for a postdoctoral associate to study #nucleotide metabolism in physiology and cancer in vivo! #uridine #cancermetabolism #immunometabolism Faculté de biologie et de médecine (inactif) Faculté de biologie et de médecine (inactif) Department of Immunobiology at UNIL 🔗(PDF): jourdainlab.org/wp-content/upl…

🎉Excited to announce job openings in our new lab at @MPI_Bio /FML in Tübingen!🇩🇪Looking for enthusiastic colleagues to explore regeneration together! We have positions for: 🔬Research Technician 💻Bioinformatician 🎓PhD studentship 🧪🔬📖 Postdoc Details and links below👇

Stoked to share TWO preprints on mitochondrial pearling! 🎉 We uncover how spontaneous #mitochondria pearling drives #mtDNA nucleoid distribution (doi.org/10.1101/2024.1…), and Gabriel (Gav) Sturm et al. dissect the biophysics behind it (doi.org/10.1101/2024.1…). Details below! 🔬🧵

🚨Why can’t mammals regenerate legs or arms like frog tadpoles or salamanders? Our preprint tackles (part of) this BIG question with surprising findings about oxygen sensing 🔗biorxiv.org/content/10.110… Happy New Year, everyone! 🎉 🐭 vs 🐸 #evodevo #regenerative #cellbio 🧵👇

📢We're recruiting📢 Our lab at the University of Lausanne is looking for a postdoctoral associate to study #nucleotide metabolism in physiology and cancer in vivo! Please share #uridine #cancermetabolism #immunometabolism Faculté de biologie et de médecine (inactif) Université de Lausanne 🔗(PDF): jourdainlab.org/wp-content/upl…

I’m happy to share the latest work from my postdoc, just published in Nature Communications! We show for the first time in vivo the critical involvement of SLC15A4/TASL complex in endosomal TLR immune responses through IRF5 activation. nature.com/articles/s4146… #innateimmunity #autoimmunity

Check out our new pre-print from the Alexis A. Jourdain ! How do growth and death screens compare when uncovering novel regulators of mitochondrial function? Is Ménière disease a mitochondrial disorder? Find out below 👇

2 weeks left to apply to the postdoc position in our lab AND we are extending the call to 2 topics! ➡️ nucleotide metabolism in #immunometabolism and #cancer in vivo ➡️ mitochondrial RNA granules in #innate_immunity Same link: jourdainlab.org/wp-content/upl… Faculté de biologie et de médecine (inactif) mitojobs

Postdoc position in the Jourdain Lab!

The latest pre-print from the lab is out! 🥳 In this work led by our PhD student Abigail, the Alexis A. Jourdain adds a piece to the puzzle of mechanisms balancing #pyrimidines and #purine synthesis, and hints at #NUDT5 expression as a potential predictor of chemotherapy resistance.

Pint of Science was again a great success in Lausanne, with >500 people attending our events! Kudos to co-coordinators Miriam Lisci and Julien Luneau, and to the fantastic team of 19 volunteers at the bars 🥳! #PINT25 #scicomm