New insights on what stimulates long-lived antibody production could spur better vaccines search.app/Jyb8stEJ4VVEcZ…

Using single-cell RNA sequencing, imaging mass cytometry and spatial transcriptomics, we mapped the immune-stromal shifts fueling tumor growth. Key players: 4-1BB+ Tregs, CXCL13+ exhausted T-cells, SPP1+ macrophages and TLS dynamics.

We have to stand up for science! Anyone who can join these rallies and believes that US science must be defended should come! I’ll be there in DC - join me!

Spatial omics data starting to show some good clinical utility: "Spatial immune scoring system predicts hepatocellular carcinoma recurrence" nature.com/articles/s4158… likely the tip of the molecular iceberg nature

FDA grants accelerated approval to telisotuzumab vedotin-tllv for advanced non-squamous NSCLC with high c-Met overexpression. Discover more: t.ly/IH8cc #LARVOL #CancerResearch #Oncology #CancerData #ClinicalTrials #OncologyInsight #PrecisionOncology #NSCLC #LCSM |

Excited to share our comprehensive pan-cancer analysis of the tumor microenvironment. Led by Bhavneet Bhinder, Paul Spellman & collaborators, we mapped the TME of >10,000 tumors, revealing 41 distinct immune/stromal patterns and their link to survival nature.com/articles/s4159…