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Why are people talking about TPE? instagram.com/p/DKLqjA4xBLC/

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"Exciting milestones are being celebrated by the Dog Aging Project as the first canine participants graduate from the groundbreaking Test of Rapamycin in Aging Dogs (TRIAD) clinical trial." Read the full article to learn more: citydogmagazine.com/dog-aging-proj… #dogs #DogAgingProject

What's your favorite longevity myth? I'm starting a collection: instagram.com/p/DKX-GOwyKhk/

Today's longevity myth: FDA won't approve a drug that slows aging, because aging is not recognized as a disease. instagram.com/p/DKa6wFFxufJ/

The response from Matt Kaeberlein to a the question about NMN and why it's bad: "I wouldn't say NMN is necessarily "bad" although there is one study showing evidence that it causes kidney damage in aged animals. No data I'm aware of in humans on that. Leaving that risk out, there

Why does lifestyle impact so many different diseases?

Todays Longevity Myth: Aging research is adequately funded. instagram.com/p/DKcm4RYyl0v/ Thanks Anthony M. Hopper for the suggestion!

Today's Longevity Myth: Resveratrol is a longevity molecule You knew this one was coming, right? It's hard for me to believe how many people still think resveratrol is a longevity supplement. The scientific community moved on more than a decade ago, but some high profile

New episode of the Optispan Podcast just dropped. Microbiome expert Sean Gibbons from ISB sits down with me to decode the complex world of gut bacteria. Learn about good vs. bad bacteria, the impact of antibiotics and aging, and how diet and probiotics can influence your

Here's the problem: scientists should not claim to be able to quantify something they can't actually measure. This is a nice study and adds value. However, the work from Arun Balachandran (@arunabc3.bsky.social) Daniel Belsky and colleagues does not quantify biological age or biological aging rate. At

Huh, I feel like I've been saying exactly this for at least 5 years now... We still don't have anything better than rapamycin as a longevity drug and nothing close to 1990s caloric restriction at all. Would be great to get some real discovery science going to find new, large

Todays Longevity Myth: Your longevity is mostly determined by your genes. Less than 50% of longevity is inherited, and it's probably closer to 25% for most people. That means you have the power to greatly influence your own longevity and healthspan trajectory.

Why can't we do better than caloric restriction? From Matt Kaeberlein's talk at the NUS Gerophysics conference. Full video here: youtube.com/watch?v=hySlWn…

I need to update this with some new interventions, but the message will be the same. Other than CR, nothing is better than rapamycin for longevity (in mice) and nothing comes close to CR. Metformin, intermittent fasting, and nicotinamide riboside have lifespans essentially