Today Matt Nelson and I have posted to medRxiv an analysis showing that labeled side effects of approved drugs are enriched for genetic evidence medrxiv.org/content/10.110…

Published today, our reasons for optimism that success rates in drug discovery can be improved by picking the right targets using human genetics: nature.com/articles/s4158… I break the key findings down panel by panel in this thread: x.com/cureffi/status…

Lightning summary: - Drug programs supported by human genetics are more successful, almost regardless of the nature of the genetic evidence - Increase in success rate may be especially large for disease-modifying therapies - Genetics still underutilized in picking targets

Tweet, tweet

Now I can tweet from my Blackberry app. Of course, nobody gives a rip. If you tweet and nobody reads it, do you make a sound?

#DYK #genomics is helping us predict disease? Can our genes help find new #medicines too? We’re hosting a #hackathon w/ Open Targets BioData World to see what the data will show 🔍