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Arabidopsis mutants unexpectedly connect mitochondrial RNA processing to the control of cell division and growth as their roots grow and develop their shape elifesciences.org/articles/61611…

Eric's talk from the Open Box Science session this week is up on YouTube if anyone's interested in hearing about our ENCODE RBP work

The PPR domain of mitochondrial RNA polymerase is a ribonuclease required for mtDNA replication biorxiv.org/cgi/content/sh… #bioRxiv

The findings of a study in Nature raises the possibility that eukaryotes with mitochondrial remnants may secondarily acquire energy-providing endosymbionts to complement or replace functions of their mitochondria. go.nature.com/3rsnU8X

Analogies abounded as 10 NIEHS fellows sought creative ways to explain their research in three minutes or less during the sixth annual Big Picture, Small Talk competition. factor.niehs.nih.gov/2021/3/beyond-…

Here's our take on the ongoing madness! Visualising formation of the ribosomal active site in mitochondria nirupa desai @BurtonNick Hanting Yang (杨涵婷) Eric Miska Eric Miska Lab biorxiv.org/content/10.110…

Way to go Bart Bartosz Orzel, MD MSc! Congratulations of this big accomplishment!

Tagging of cellular complexes with #CRISPR allows purification for #cryoEM. With @YueLabOX and Ville Paavilainen 🇫🇮🇺🇦 our structures of endogenous TRiC chaperonin reveal interactions with its substrates actin and tubulin biorxiv.org/content/10.110… STRUBIOxford Institute of Biotechnology (BI) HiLIFE_Helsinki

Dr. Tony Mustoe (Tony Mustoe, Baylor College of Medicine, mustoelab.org) speaks at our monthly seminar on Tuesday, April 13, 2021, at noon. The title is 'Discovery of large-scale RNA structural dynamics in living cells.'

Protein identification from electron cryomicroscopy maps by automated model building and side-chain matching scripts.iucr.org/cgi-bin/paper?…

Excited to share our work on DNA mismatch repair! Congratulations to the whole team at LUMC Leiden CNIO Stop Cancer Antoni van Leeuwenhoek Universität Gießen Erasmus MC Intl (some of us previously @MRC_LMB). Special thanks to twitterless Meindert Lamers and Titia Sixma! nature.com/articles/s4159…

Congratulations to Bartosz Orzel, MD MSc for his study published in CJC Open!! Mapping the regional variations in the association of physical activity and cardiovascular disease. This is a huge accomplishment.

Discovery of a covalent crosslink between a cysteine and a lysine residue with a NOS bridge. Beautiful structural work by the Tittmann lab Uni Göttingen. #journalclub nature.com/articles/s4158…

Excited to receive word that, along with Anita Corbett (Dr. Anita Corbett- (She/her) 🏳️‍🌈) and Michaela Müller-McNicoll (@mixmue), I have been elected as a Director of the RNA Society (The RNA Society) for 2022-23. Eager to serve the worldwide RNA research community in this capacity!

Our latest story on the molecular acrobatics of SRP and its receptor during protein targeting to the ER and how it's perturbed in disease, check it out today Science Advances Another great collaboration with the Shan lab! The Ban Lab advances.sciencemag.org/content/7/21/e…

Today in #journalclub: the power of detergents in overcoming the common problem of preferential particle orientation in cryo-EM. Two take home messages: consider the detergent charge and the critical micelle concentration! biorxiv.org/content/10.110…

Happy RNA Day!

The powerhouses/overlords of the cell, mitochondria (yellow), and DNA in the nucleus (blue) videoed through a microscope. #CellBiology #microscopy #SciArt

Registration is still open for the TMC Jr. Faculty Extravaganza event! Don't miss it! #gccjrfac2022

Great visiting a fellow @NIEHS alumni, Pillon Lab, and checking out all the cool science BCMHouston! I love in person seminar visits and missed them. Will have to come back and explore more of Houston sometime.