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Very cool deep mutational scanning strategy to better understand a key player in RAS biology. Congrats Jason Kwon and team!

A perfect day for a picnic with this spectacular lab family! I hear there is a volleyball team in the making 😊😊😊

The sunk-cost fallacy is that when you have invested heavily in something you tend to be willing to invest more in the same thing and to resist abandoning it. But to be creative, you need to have zero sunk cost. You should always be willing to start over. nightscience.buzzsprout.com/1744020/113662…

Check out Kavita Rangan’s work in this new preprint from our lab! We show that wild squid rapidly employ RNA recoding to generate unique kinesin motor variants in different ocean temperatures. doi.org/10.1101/2022.0… 1/

We are looking for postdocs or graduate students BBS at Harvard to join our team! If you're interested in applying functional genetics/integrative genomics to study cancer, please contact me. Check out lab website viswanathanlab.dana-farber.org or apply here: careers-dfci.icims.com/jobs/31228/res…

Congratulations Daniel Bondeson! This is a great resource that I’ve found really helpful in degron tagging proteins!

Thrilled to announce that I will join the faculty of the Brigham & Women’s Hospital Division of Hematology and Harvard Medical School Jan 2023. The Hollenhorst research group will study glycoproteins that play key roles in bleeding and clotting disorders. @BrighamHeme

“There are up to 400 million people worldwide affected by one of the 7,000 diseases caused by mutations in single genes.” nyti.ms/3iKqtnf

Congratulations Marie Hollenhorst, MD, PhD. Very excited to have you back in Boston! You’ll be an incredible mentor!

Excited to share our new publication. Using The Cancer Dependency Map data, we found that BIRC6 is required to suppress the ISR pathway and maintain survival in a subset of epithelial cancers. Check it out!

Check out two new publications on Ewing sarcoma and ETV6 in Nature Cell Biology from our lab and Christopher Vakoc. Excited to see them both in press! doi.org/10.1038/s41556…

ONLINE NOW Nature Cancer “Understanding inequities in precision oncology diagnostics” – a Perspective by #FranklinWHuang, Tim Rebbeck & CO. Don’t miss it👇 nature.com/articles/s4301… rdcu.be/ddrMY

1/5 Genomics 2 Proteins v2.5 released! New features - #AlphaFold2 structures and structural features for full human proteome, UniProt annotations in table view and data download, Atlas of Variant Effects Alliance data, and #ClinVar update (2023 03; 1,626,964 variants!). g2p.broadinstitute.org

Thank you Damon Runyon Cancer Research Foundation! This is an amazing program to support physician-scientists and I'm grateful to be a part of such an amazing community of researchers working to tackle tough problems in cancer.

Can't wait!

We are happy to share our latest long-range, programmable mutagenesis toolbox - the Helicase-Assisted Continous Editing (HACE) system - to achieve target-specific mutagenesis of the endogenous genome. (1/11) biorxiv.org/content/10.110…

🔥New episode comes out today! Todd Golub is the Director of the Broad Institute. For him, creativity is the greatest hallmark of a successful scientist, and he aims to hire researchers who will be switching fields in the future. podcasts.apple.com/us/podcast/tod… Itai Yanai Martin Lercher