🔥The 9th Round of Easy Loan, Earn $40 Reward is in progress❗️ ⏰ Promotion Period: January 15th - Feburary 15th, 2025 👉 Register now and check more details at gate.io/campaigns/358

Converging view that nucleotide excision repair is often the source of mutations. Found in bacteria doi.org/10.1101/2022.0…, cancer doi.org/10.1101/2022.0… and building on insights from yeast doi.org/10.1534/geneti…. Houra Merrikh biorxiv adds bacterial and evo. perspective

Our preprint about the role of POLD1 deficiency in soma and germline mutations is out. biorxiv.org/content/10.110… Two main findings: surprisingly, POLD1 deficiency has a recessive effect on mutation rate; POLD1 alters mutational spectra to the same degree in soma and sperm

Earlier this week, John Connelly and Jose Coelho-Lima both gave talks at #ECP2022Basel Here is John's brilliant talk on "Predicting genetic variation from quantitative tissue phenotypes using explainable machine learning" #MachineLearning #DigialPathology #GenomicPathology

Discussions at our Bertinoro Computational Biology (of Cancer) meeting #BCB22 were fab. We finished our meeting by summarising these into a "top 5 open research questions". I'll tweet the list with hashtag #BCB22_Qs. We're interested to hear your thoughts (even solutions!)

🧑🏾‍🔬We're looking for an ambitious, curious, smart, team-playing #postdoc to join Aitken Lab MRC Toxicology Unit Cambridge University 🧬DNA damage, mutagenesis, genome biology, (spatial) genomics 🌍New labs in central Cambridge 🗓Deadline: 24 Oct 2022 📩Apply: jobs.cam.ac.uk/job/37242 Please RT

It took a few years, with a global pandemic and transatlantic relocation in the middle of it. But finally, our manuscript on how UV irradiation remodels the specificity landscape of transcription factors is on BioRxiv biorxiv.org/content/10.110…. Huge thanks to...

⏰One week left to apply for the postdoc position Aitken Lab MRC Toxicology Unit Cambridge University jobs.cam.ac.uk/job/37242/

We are recruiting 30 - yes, that's right, 30! - Chancellor's Fellows to prestigious, tenure-track, research-intensive early/mid-career roles at the University of Edinburgh. Please spread the word!

..and check out the Alumni from the Edinburgh Scientific Academic Track, who now have open-ended faculty positions. ed.ac.uk/medicine-vet-m…

Now that I've had a chance to see peoples' questions about eLife - the journal's new publishing model, time for a thread for a thread with some details and answers. elifesciences.org/articles/83889

A great opportunity...

🧬Are you interested in DNA, mutations, and keeping patients safe? 🧑🏿‍🔬We're looking for a curious, smart, ambitious, team player to join us in October 2023 💊AstraZeneca-Funded PhD Studentship with industrial placement 🗓️Closes: 05 Dec 2022 jobs.cam.ac.uk/job/37892/ Please RT!

Are you a graduate level physicist, mathematician, computer scientist or similar that can make a difference in biomedical research? Apply by January 9 2023 for Medical Research Council funded PhD projects for quantitative scientists and join us in Edinburgh! ed.ac.uk/mrc-human-gene…

Apply by January 9 2023 for our #PhD programme in Human Genetics, Genomics and Disease. Join us in Edinburgh to develop your research career and tackle key problems in understanding how our DNA affects health and disease Institute of Genetics and Cancer ed.ac.uk/mrc-human-gene…

Tomorrow, John Connelly will be sharing his exciting new #pathomics findings: "Using #MachineLearning and #ComputationalPathology to explain unexpected genomic variation" Still time to register for this hybrid event RC of Pathologists: web.cvent.com/event/5a353be6…

I'll be at the GRS and GRC on Mammalian DNA Repair 2023 with a poster on lesion segregation and muliallelism. Come and find me for a chat!

Today is the last day of abstract submission for Mutations in Time and Space. mutationmeeting.com Join us in stunning Edinburgh, 23-25 April 2024, to present your latest research.

🎉New paper🎉Introducing #StrandInteractions, the sequel to #LesionSegregation, published today nature Strand-resolved mutagenicity of DNA damage and repair nature.com/articles/s4158… Here’s what we discovered about (a)symmetry in replication, transcription & #mutagenicNER [1/13]

Now out nature, our paper on HiDEF-seq: single-molecule DNA sequencing that resolves single-strand changes (mismatches and damage)! go.nature.com/3KG7Njh