🔥The 9th Round of Easy Loan, Earn $40 Reward is in progress❗️ ⏰ Promotion Period: January 15th - Feburary 15th, 2025 👉 Register now and check more details at gate.io/campaigns/358

Acetylation fuels aggregation of three-repeat tau yet slows that of four-repeat tau. Why? Acetylated lysines in a segment unique to 4R tau disrupt fibril cores. @DZNE_en ow.ly/bbRK50PUbkb

What is the connection between synaptic dysfunction in #AlzheimersDisease and #Tau? PhD student Zheng Shen in collaboration with the lab of Alf Honigmann shows that Tau induces changes in the material properties of post-synaptic density #condensates nature.com/articles/s4146….

Saddened to hear of the passing of Tony Keller aged 86, a pioneer in NMR technology and former director of Bruker and co-CEO of Bruker BioSpin. Tony was a great supporter and friend to many in the #NMR field and we will miss him. #biophysics #chemistry bruker.com/en/news-and-ev…

Vielen Dank for the speech, rooted in knowledge and striking a well-balanced yet comprehensive, clear and empathetic tone. Such leadership gives hope for a unified stance among all nationalities to renounce hatred and embrace the greater good.

Tina Ukmar-Godec and coworkers from my lab show in a collaboration with the Fischle Lab that phase separation of human HP1alpha is not necessary to compact chromatin

A direct link between Tau phosphorylation by GSK3beta, #Tau condensation and #AlzheimersDisease 's Disease Tau Fold: stellar work from Pijush Chakraborty in collaboration with the lab of Ben Wolozin biorxiv.org/content/10.110…

Good point. We see (i) that GSK3b phosphorylation accelerates aging of tau condensates and (ii) fibrils of unphosphorylated tau have a different morphology, suggesting that the GSK3b phosphorylation is critical.

ICMRBS 2024 the 30th International Conference on Magnetic Resonance in Biological Systems (ICMRBS 2024) | August 18 (Sun) - 23 (Fri), 2024 | Coex, Seoul, Korea icmrbs2024.org/main/bbs_news_… #NMRevents #NMRchat #NMR

Thanks Sjors. This is how good we could get the structure with the available data.

Ending 2023 in style: Hsp90-Independent cochaperone-mediated regulation of Tau aggregation: fantastic work from Pijush Chakraborty doi.org/10.1101/2023.1…

Dear international students and talents from around the world, note that German universities welcome foreign students, are tuition free and many subjects are taught in English. Germany has become an open and liberal society in contrast to what the UK government is implementing.

Congratulations Samrat!

Comparison of four transcription elongation factors reveals conserved regulatory mechanisms. New review by Ying Chen sciencedirect.com/science/articl…

Pat, did you get my email?

Very much looking forward to this exciting meeting!

In a just published article in #NatureComms, we report droplet formation by an RG-rich fragment of coilin, a protein acting as the scaffold of Cajal bodies (CBs). CBs are highly dynamic nuclear bodies with rapid component exchange, supporting RNA splicing. link.springer.com/article/10.103…

This is a major milestone for the diagnosis and treatment of Alzheimer’s. The ptau-217 blood test is shown to be as accurate as CSF and PET, making diagnosis far more accessible. And detecting AD before observable symptoms will enable much earlier intervention.

An enormous thank you to my fantastic team, co-workers, collaborators and the European Union for making this possible , and my Kids Magdalena and Maximilian for their inspiration. dzne.de/en/news/press-…

Check out the enticing and diverse Scientific Program of #SMASH2024 (Burlington, VT, USA - September 15-18, 2024) put together by Kathleen Farley Kathleen Farley and myself, the Program Chairs. We've assembled seven sessions, two workshops, led by 17 speakers. smashnmr.org

Interested in translational science? 🧪 Our team at #DZNE Munich is seeking a technician for the GA-VAX project. Your work could directly contribute to clinical trials with #C9orf72 #ALS patients. Apply now and join our team! #Jobs #Research jobs.dzne.de/de/jobs/101347…