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I'm super excited to share that our work on clonal hematopoiesis in the tumour microenvironment is now published in Cell Reports Medicine!! By tracking CH mutations from the blood into the tumour (CH-Tum), we uncovered some new insights about CH in solid cancer cell.com/cell-reports-m…

Alex Bick, Kun Zhao, and I are excited to share our preprint describing mosaic chromosomal alterations (mCAs) across 1 million people in Vanderbilt BioVU, UK Biobank, NHLBI TOPMed, and NIH All of Us. Co-tweetorial from Kun and me to follow! medrxiv.org/content/10.110… 1/8

Well this is cool! 😎

📢Our department, Cancer Epidemiology, is hiring. All strong applicants will be considered. Come work with us! Moffitt Research Moffitt Cancer Center …cancer-center-careers.hctsportals.com/jobs/1946077-t…

#Myeloma Paper of the Day: Impact of clonal hematopoiesis on clinical outcomes to BCMA CAR-T in myeloma includes higher risk of prolonged transfusion dependence for both pRBC and G-CSF us, as well as higher thrombopoietin receptor agonist use: pubmed.ncbi.nlm.nih.gov/40203191/. #mmsm

Metformin reduces the competitive advantage of Dnmt3aR878H HSPCs | Nature nature.com/articles/s4158…

Wow, today is the day...excited to see this amazing work from Daniel Starczynowski and his lab out! The microbiome of clonal hematopoiesis patients! nature.com/articles/s4158…

It’s not just a blood cancer problem. When CH impacts all cancers ! 👇🏾👇🏾

Such an awesome talk to open the second day of an awesome symposium👏🏻🙌🏻

Fascinating science & story around an ageing gut & interaction with CHIP clones by Daniel Starczynowski . Such cool science & potential for more studies to tease out its role in leukemic evolution UMiami Health System Sylvester Comprehensive Cancer Center

In our new preprint, our findings challenge the cancer stem cell hierarchy in B-ALL. Instead, we show that subpopulation dynamics are better explained by spontaneous, reversible cell state transitions. 🔁 Plasticity > hierarch biorxiv.org/content/10.110…

Soaking in the brilliance of Dr. Anthony Stephen Fauci at #ASCPT2025

New paper in The Lancet eClinicalMedicine with James Brogan & Ashwin Kishtagari, MD Vanderbilt Health We found that cytopenia is a key step from #CHIP ➡️ myeloid neoplasm (MN). Cytopenia-free survival = a new CHIP trial endpoint? doi.org/10.1016/j.ecli…

Remarkable work by Yash Pershad and team on CHIP dynamics over 16 years in ~7,000 women out now in Blood Journals Portfolio! Longitudinal CHIP studies remain rare - this depth of follow-up is invaluable. Correlates and Consequences of Clonal Hematopoiesis Expansion Rate: A 16-Year

🚨 New paper in Nature Genetics ! How does cancer chemotherapy reshape the HSC landscape and drive the evolution of therapy-related myeloid neoplasms? We uncovered this process through single-colony WGS! See the full paper here! nature.com/articles/s4158…

This work appears back-to-back with a powerful study from Jyoti Nangalia and Mike Stratton (Wellcome Sanger Institute) profiling the impact of wide array of cytotoxic therapy on human hematopoiesis. 🔗 nature.com/articles/s4158…