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A sign of maturity is caring more about being respected than being liked. Liking is shallow affection. It comes from being pleasant—you bend over backwards to accommodate others. Respect is deep regard. It's earned by being principled—you consistently stand up for your values.

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People get frustrated when trying to solve isolated problems because they are often a source of system problems. Systems thinking is essential when addressing any isolated problem. Ask better and broader questions for more sustainable solutions. x.com/i/grok/share/S…

Routine use of rifampin in not recommended for staphylococcal native valve endocarditis. But what if patient undergoes valvular surgical intervention? The answer is still no. Not only does rifampin combination therapy not help, it may cause harm. academic.oup.com/ofid/advance-a…

New review article on management of S. aureus bacteraemia: jamanetwork.com/journals/jama/… JAMA Check out the gorgeous Figure which brings together elements of pathogenesis and management: (thread)

Trigger warning ⚠️ Ceftriaxone isn’t de-escalation in many clinical scenarios

Failure is thinking you know it all. Success is admitting you don’t and seeking small wins over a long time horizon. What’s one thing you’ve learned today?

This is how it feels to leave Costco only buying what you had on your list

Colon cancer is on the rise around the world. This new report concludes that early-life exposure to gut bacteria that produces colibactin, which is mutagenic, may be contributing nature.com/articles/s4158…

Our real world study is the 1st (to our knowledge) to detail widespread restriction of remdesivir with patients that represent present-day epidemiology in the era of near universal SARS-CoV-2 seropositivity. In CID 📖 Brent Footer Betsy Hirsch, PharmD (TTIDPD) #IDTwitter academic.oup.com/cid/advance-ar…

What's a belief you no longer hold? I used to think being 100% selfless was ideal. Now I know it can lead to overextending & misalignment. Be a bit selfish to protect your time and match demands with skills/interests. But always be kind.

“If you cannot be corrected without being offended, then you’ll never truly grow in life.” — Richard Feynman

Hot takes 🧠 🦠 1) Linezolid >> vanco as the preferred second agent w/ ceftriaxone for empiric coverage of community-acquired meningitis 2) Do most pts need the second agent with high susceptibility rates for CRO to common bacterial causes of meningitis? Thoughts?

Another 🔥 take: There’s an overconfidence in clindamycin and its role in practice. For most indications: A) better options often exist (linezolid) OR B) better questions should be asked (are you REALLY allergic to the primary treatment options?) AND C) resistance a problem

There’s a few certainties I’ve embraced: 1) Curious minds prevail👇 2) Change is certain 3) Too many operate out of fear 4) We thrive via human connection 5) Having kids is the greatest joy 6) You get what you’re willing to work for 7) Faith is essential What did I miss?

Next 🔥 take For most patients, metronidazole should be dosed either once or twice a day (IV or PO), using a TDD of 1,000 mg/day Where would you feel uncomfortable using this dosing?

Often we don’t need more people, we need better processes and resource allocation. Most importantly, ask better questions.❓

Heads up, GoodRx is trying to trick pharmacies into signing up for a webinar in which the pharmacies would waive their right to sue GoodRx. DO NOT SIGN UP

One’s inability to be open-minded significantly stifles growth potential.